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Updated: Feb 10, 2026

Preparation of Binary and Ternary Deep Eutectic Systems
Published on: October 31, 2019
A novel and simple deep eutectic solvent based liquid phase microextraction method for rhodamine B in cosmetic
Erkan Yilmaz1, Mustafa Soylak1
1Erciyes University, Faculty of Sciences, Department of Chemistry, 38039 Kayseri, Turkey.
Abstract:
A novel and green deep eutectic solvent based liquid phase microextraction (DES-LPME) methodology has been proposed for the assessment of rhodamine B from cosmetic products and water samples. A deep eutectic solvent (DES) consist of tetrabutyl ammonium chloride-decanoic acid (1:2) as extraction solvent and tetrahydrofuran as emulsification agent were used for the microextraction of rhodamine B. The quantitative recoveries were achieved at pH 3 by using 0.3 mL of DES and 0.3 mL of THF. The rhodamine B concentration in last volume was analyzed by mirco-cuvette UV-VIS spectrophotometer at 550 nm. The limit of detection (LOD), limit of quantification (LOQ), preconcentration factor (PF) and relative standard deviation (RSD %) were found as 2.2 μg L-1, 7.3 μg L-1, 25 and 2.3%, respectively. Accuracy and validity of the developed method was verified by addition-recovery studies for water and cosmetic samples.
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