Non-invasive measurements to stratify cardiovascular disease risk in psoriasis patients

Philippa Dickison1, Jonathan J Peek2, Grace Swain3

  • 1MD, PhD candidate, Sydney Medical School, University of Sydney, Sydney, NSW; Department of Dermatology, Royal North Shore Hospital, St Leonards, NSW. philippa.dickison@sydney.edu.au.

Insights

Patients with psoriasis face higher cardiovascular disease (CVD) risks, including obesity and blood pressure issues. Many are unaware of these serious comorbidities, highlighting a critical knowledge gap.

Area of Science:

  • Dermatology
  • Cardiology
  • Public Health

Background:

  • Psoriasis is linked to increased cardiovascular disease (CVD) risk factors and mortality.
  • Understanding CVD risk and patient awareness in psoriasis is crucial for preventative care.

Purpose of the Study:

  • To assess cardiovascular disease (CVD) risk in patients diagnosed with psoriasis.
  • To evaluate the awareness level of psoriasis patients regarding associated comorbidities.

Main Methods:

  • Anthropometric measurements (inter-arm blood pressure, weight, height, waist circumference) were taken for psoriasis patients and controls.
  • Psoriasis patients completed a survey on their awareness of associated health conditions.

Main Results:

  • Psoriasis patients were significantly more likely to be obese (OR 6.3).
  • An inter-arm systolic (OR 1.9) and diastolic (OR 2.3) blood pressure difference >10 mmHg was more common in psoriasis patients.
  • Only 26.3% of psoriasis patients were aware of the link between psoriasis and being overweight.

Conclusions:

  • Patients with psoriasis exhibit elevated CVD risk based on anthropometric data compared to non-psoriasis individuals.
  • There is a significant deficit in knowledge among psoriasis patients concerning their condition's comorbidities.
Abstract

Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
580
Stratified Sampling Method01:16

Stratified Sampling Method

Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
To choose a stratified sample, divide the population into groups called strata and then take a...
15.5K
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.2K
Overview of the Cardiovascular System01:14

Overview of the Cardiovascular System

The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
12.1K
Classification of Epithelial Tissues: Stratified Epithelium01:29

Classification of Epithelial Tissues: Stratified Epithelium

Stratified epithelium consists of several stacked layers of cells. They provide the durability to withstand constant physical and chemical attacks. Stratified epithelium is named after the shape of the most apical layer of cells. Stratified squamous epithelium is the most common type found in the human body. In this tissue, the apical cells are squamous, whereas the basal layer contains either columnar or cuboidal cells. The basal cells divide to form new daughter cells, which gradually become...
13.0K
Regulation of the Cardiovascular System01:27

Regulation of the Cardiovascular System

The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
4.1K