Related Experiment Video For Bioelectrical impedance analysis
Updated: Feb 10, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
Resistive Part of Impedance as a Possible Indicator of Hepatocellular Carcinoma
Jeny Salazar-Anguiano1, María de Guadalupe Chávez-López2, Violeta Zúñiga-García2
1Departamento de Ingeniería Eléctrica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de México, México.
Background And Aims:
In this work, the multi-frequency impedance both in normal and liver cancer tissues was studied. This was to investigate the feasibility to detect liver cancer by a low cost, easy to use, and a relatively non-invasive electrical impedance measure technique, and thus potentially improving liver cancer diagnosis.
Methods:
Hepatocellular carcinoma (HCC) was induced in male Wistar rats by the administration of diethylnitrosamine (DEN) during 16 weeks. The electrical impedances at a frequency sweep of 10-100 KHz in the whole body and 10-60 KHz in the liver were taken at the end of the treatment.
Results:
The electrical impedance showed that the real component values of the impedance change in HCC. In addition, we found that the imaginary component was not associated with HCC.
Conclusion:
Our results suggest that the electrical impedance may be used as a diagnostic HCC tool.
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