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Updated: Feb 10, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Treatment of progressive multiple sclerosis: Challenges and promising perspectives
1Department of neurology, Pitié-Salpêtrière hospital, AP-HP, 47-83, boulevard de l'Hôpital, 75013 Paris, France.
Abstract:
Management of progressive multiple sclerosis (MS) is one of the main challenges of the new century. Based on our knowledge of pathophysiology, three therapeutic strategies are proposed: anti-inflammatory (ocrelizumab, siponimod…); remyelinating (opicinumab); and neuroprotective (high-dose biotin, ibudilast, simvastatin…). Nevertheless, despite recent promising positive clinical trials, new methodological approaches for therapeutic protocols with adaptable outcomes to assess progression are still needed.
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