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Updated: Feb 10, 2026

Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis
Enrico Coppola Bottazzi1, Adele Noviello1, Nicola Moles1
1Department of Oncological and General Surgery, S.G. Moscati Hospital, Avellino, Italy.
Introduction:
Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk.
Case Report:
We report a case of Merkel's abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE® BIO-A®.
Discussion:
Immunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin. MCC is an aggressive tumor with poor prognosis.
Conclusions:
For primary tumors without indications of the presence of organ metastases complete surgical excision is the gold standard. Gore BIO-A is a biosynthetic prosthesis with manageable structure that allows it to be positioned and shaped according to needs, its strength provides for excellent support for the reconstruction of the inguinal canal wall.
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