Prediction of preeclampsia developing at term.

Area of Science:

• Obstetrics and Gynecology
• Maternal-Fetal Medicine
• Perinatal Research

Background:

• Preeclampsia is a serious pregnancy complication.
• Preterm preeclampsia (PE) is predictable and preventable with aspirin at 11-13 weeks.
• Term PE, though more common, lacks effective early prediction and aspirin prevention.

Purpose of the Study:

• To review the pathogenesis of term PE.
• To discuss current and potential strategies for predicting term PE.

Main Methods:

• Literature review on term PE pathogenesis.
• Analysis of existing and proposed prediction methods for term PE.

Main Results:

• Term PE pathogenesis is complex and distinct from preterm PE.
• Current early prediction methods are ineffective for term PE.
• Aspirin prophylaxis is not effective for preventing term PE.

Conclusions:

• Term PE poses significant maternal risks.
• Effective prediction of term PE remains a challenge.
• Further research into term PE prediction strategies is crucial.