Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sex-linked Disorders01:43

Sex-linked Disorders

109.2K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
109.2K
Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

641
During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
641
Electric Potential and Potential Difference01:16

Electric Potential and Potential Difference

5.8K
Suppose a positive test charge moves away from a positive static charge, then the Coulomb force does positive work, and its electric potential energy decreases. The potential energy per unit charge is defined as the electric potential. The electric potential is independent of the test charge.
When a test charge moves from the initial to the final position, the electric potential difference between those positions is defined as the ratio of the change in the potential energy to the charge on the...
5.8K
Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

8.4K
The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
8.4K
Identifying Statistically Significant Differences: The F-Test01:14

Identifying Statistically Significant Differences: The F-Test

3.9K
The F-test is used to compare two sample variances to each other or compare the sample variance to the population variance. It is used to decide whether an indeterminate error can explain the difference in their values. The underlying assumptions that allow the use of the F-test include the data set or sets are normally distributed, and the data sets are independent of each other. The test statistic F is calculated by dividing one variance by another. In other words, the square of one standard...
3.9K
Sum and Difference OpAmps01:22

Sum and Difference OpAmps

1.4K
Operational amplifiers (op-amps) are versatile devices that extend beyond amplification. In this context, two specific op-amp configurations are explored: the summing and difference amplifiers.
A summing amplifier, or an adder, utilizes an op-amp to merge multiple input signals into a single output signal. When audio signals are introduced into its input channels, the input resistors initiate currents that traverse feedback resistors, resulting in an output voltage. Applying Kirchhoff's current...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Androgen depletion increases sensitivity to effort-related costs and alters mesoaccumbal circuit function in male mice.

bioRxiv : the preprint server for biology·2026
Same author

Thrombosis in adult primary immune thrombocytopenia in Korea: incidence and risk factors in a 20-year retrospective cohort.

Annals of hematology·2026
Same author

Lenvatinib plus pembrolizumab versus standard of care in recurrent/metastatic head and neck squamous cell carcinoma: Randomized, phase 2 LEAP-009 trial.

European journal of cancer (Oxford, England : 1990)·2026
Same author

TiON/NiO<i><sub>x</sub></i> Heterojunction Neuron for CMOS-Compatible Hardware Implementation of Activation Function in Neural Network.

ACS applied materials & interfaces·2026
Same author

Energy- and Area-Efficient Ionic-Switch Activation Neuron for Monolithic 3D Neural Network Architectures.

ACS nano·2026
Same author

Therapeutic Efficacy of PB101 and Chemotherapy Combination in Preclinical Gastric Cancer Models.

Anticancer research·2026

Related Experiment Video

Updated: Feb 10, 2026

Administration of &#916;9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

1.1K

Sex differences in adolescent ethanol drinking to behavioral intoxication.

Sara R Westbrook1, Minsu Kang1, Luke K Sherrill1

  • 1Department of Psychology, University of Illinois at Urbana-Champaign.

Journal of the Experimental Analysis of Behavior
|May 22, 2018
PubMed
Summary

Adolescent rats readily consumed ethanol, showing intoxication. Females exhibited increased impulsive actions after abstinence, indicating sex differences in ethanol

Keywords:
consumptionethanolimpulsive behaviornose pokerat

More Related Videos

Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia
08:32

Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia

Published on: October 25, 2016

13.9K
Microdialysis of Ethanol During Operant Ethanol Self-administration and Ethanol Determination by Gas Chromatography
10:11

Microdialysis of Ethanol During Operant Ethanol Self-administration and Ethanol Determination by Gas Chromatography

Published on: September 5, 2012

18.1K

Related Experiment Videos

Last Updated: Feb 10, 2026

Administration of &#916;9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

1.1K
Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia
08:32

Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia

Published on: October 25, 2016

13.9K
Microdialysis of Ethanol During Operant Ethanol Self-administration and Ethanol Determination by Gas Chromatography
10:11

Microdialysis of Ethanol During Operant Ethanol Self-administration and Ethanol Determination by Gas Chromatography

Published on: September 5, 2012

18.1K

Area of Science:

  • Neuroscience
  • Behavioral Science
  • Pharmacology

Background:

  • Adolescent ethanol exposure is a significant public health concern.
  • Rodent models are crucial for studying adolescent ethanol's effects.
  • Limited research exists on sex differences in adolescent ethanol intoxication behaviors.

Purpose of the Study:

  • To investigate sex differences in behavioral intoxication following adolescent ethanol consumption in rats.
  • To determine if adolescent rats of both sexes drink ethanol to the point of measurable intoxication.
  • To assess ethanol's impact on impulsive action and motor coordination.

Main Methods:

  • Adolescent male and female Long-Evans rats (postnatal day 28) were given access to ethanol or sucrose solutions every other day until postnatal day 60.
  • Impulsive action was measured by premature responding in a cued nosepoke task.
  • Motor coordination was assessed using an incline plane test before and after drinking sessions.

Main Results:

  • Adolescent rats of both sexes readily consumed ethanol, leading to measurable behavioral intoxication, including reduced motor coordination.
  • Following a period of forced abstinence, female rats showed significantly greater ethanol-induced impulsive action compared to males.
  • Ethanol consumption reliably induced motor incoordination in both sexes.

Conclusions:

  • Adolescent rats readily engage in ethanol drinking to intoxication.
  • Sex differences emerge in behavioral responses to adolescent ethanol exposure, particularly in impulsive action after abstinence.
  • These findings highlight the importance of considering sex as a biological variable in adolescent ethanol research.