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Updated: Feb 10, 2026

A Protocol for the Production of KLRG1 Tetramer
Published on: January 12, 2010
Hash-Mark-Shaped Azaacene Tetramers with Axial Chirality
Yuki Inoue1, Daisuke Sakamaki1, Yusuke Tsutsui1
1Department of Molecular Engineering, Graduate School of Engineering , Kyoto University , Nishikyo-ku , Kyoto 615-8510 , Japan.
Abstract:
The tetramers of azapentacene derivatives with unique hash mark (#)-shaped structures were prepared in a quite facile manner. The #-shaped tetramers are optically active due to possessing extended biaryl skeletons, and the structure of the tetramer composed of four dihydrodiazapentacene (DHDAP) units (1) was investigated as the first example of this kind of molecule. The tetramer 1 showed characteristic chiroptical properties reflecting its orthogonally arranged quadruple DHDAP moieties, as well as redox activity. The solution of enantiopure 1 exhibited intense circularly polarized luminescence (CPL) with a dissymmetry factor of 2.5 × 10-3. The absolute configuration of the enantiomers of 1 was experimentally determined by X-ray crystal analysis for the dication salt of the enantiomer of 1 with SbCl6- counterions. The solutions of enantiopure 12+·2[SbCl6-] also showed NIR circular dichroism (CD) spectra over the entire range from visible to 1100 nm, enabling the modulation of the chiroptical properties by redox stimuli.
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