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Suspect Screening and Regulatory Databases: A Powerful Combination To Identify Emerging Micropollutants
Pablo Gago-Ferrero1, Agnes Krettek1,2, Stellan Fischer3
1Department of Aquatic Sciences and Assessment , Swedish University of Agricultural Sciences (SLU) , Box 7050, SE-75007 Uppsala , Sweden.
Environmental Science & Technology
|May 22, 2018
Summary
Regulatory databases and high-resolution mass spectrometry (HRMS) effectively identify new aquatic pollutants. This approach prioritized and confirmed 23 previously unknown hazardous substances in wastewater, enhancing environmental monitoring.
Area of Science:
- Environmental Chemistry
- Analytical Chemistry
- Environmental Science
Background:
- Emerging pollutants pose risks to aquatic environments.
- Identifying unknown hazardous substances requires advanced analytical methods.
- Regulatory databases contain valuable information for environmental risk assessment.
Purpose of the Study:
- To demonstrate the combined use of regulatory databases and high-resolution mass spectrometry (HRMS) for identifying novel environmental pollutants.
- To prioritize chemicals for investigation based on market data and environmental exposure.
- To detect and confirm previously unrecognized hazardous substances in wastewater effluent.
Main Methods:
- Prioritization of 160 organic micropollutants from the Swedish National Product Register using market and usage data.
- Application of liquid chromatography-HRMS (LC-HRMS) suspect screening on wastewater effluent samples.
- Confirmation of tentatively identified substances using reference standards.
Main Results:
- 36 tentative identifications of organic micropollutants were achieved in wastewater effluent.
- 23 of these substances were confirmed with reference standards.
- Many identified substances were previously unconsidered by environmental scientists.
Conclusions:
- Combining regulatory data prioritization with LC-HRMS suspect screening is efficient for identifying emerging pollutants.
- This integrated approach significantly enhances the detection of potentially hazardous substances in the environment.
- Collaboration between scientists and regulatory bodies is crucial for advancing environmental monitoring and risk assessment.
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