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Related Experiment Video

Updated: Feb 10, 2026

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication

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DiaGenic ASA.

Praveen Sharma¹

¹DiaGenic ASA, Østensjoveien 15B, N-0661, Oslo, Norway. praveen.sharma@diagenic.com.

Personalized Medicine

|May 23, 2018

Summary

This summary is machine-generated.

DiaGenic ASA is developing novel blood-based gene expression tests for early disease detection. These tests show promise for identifying breast cancer and Alzheimer's disease (AD) in their early stages.

Keywords:

Alzheimer’s disease breast cancer diagnosis gene expression peripheral blood

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Area of Science:

Biotechnology
Molecular Diagnostics
Disease Biomarkers

Background:

Early disease detection is crucial for effective treatment and improved patient outcomes.
Current diagnostic methods can be invasive or lack sensitivity for early-stage diseases.
Gene expression profiling offers a potential avenue for non-invasive, early diagnostic tools.

Purpose of the Study:

To develop and validate blood-based gene expression tests for the early detection of diseases.
To leverage patented technology for identifying disease-specific gene signatures.
To create patient-friendly diagnostic solutions for conditions like breast cancer and Alzheimer's disease (AD).

Main Methods:

Mining disease-specific gene expression signatures from peripheral blood samples.
Utilizing a patented methodology for biomarker discovery.
Developing prototype diagnostic tests for clinical evaluation.

Main Results:

Demonstrated feasibility of blood-based gene expression tests for early breast cancer detection.
Successfully developed blood-based gene expression tests for early Alzheimer's disease (AD) detection.
Identified disease-specific gene expression patterns in peripheral blood.

Conclusions:

Blood-based gene expression analysis is a viable approach for early disease detection.
The patented methodology holds significant potential for diagnosing multiple diseases, including breast cancer and AD.
Prototype diagnostic tests are anticipated by late 2006, paving the way for clinical application.