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Updated: Feb 10, 2026

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
Published on: November 10, 2023
Metabolomics: a tool for personalizing medicine?
Laura K Schnackenberg1, Jim Kaput2, Richard D Beger1
1US FDA, Division of Systems Toxicology, National Center for Toxicological Research, Jefferson, AR 72079-9502, USA. richard.beger@fda.hhs.gov.
Abstract:
The concept of personalized medicine is based upon using personal genetic information to predict individual responses to drug therapy. However, environmental factors such as diet, energy status, gut microbiota, health status and age will influence the expression of one's genetic potential. Metabolomics data from biofluid and tissue sample analysis hold information regarding a patient's genotype and phenotype. Metabolomics data can be rapidly collected from biofluid samples over time, providing temporal metabolic analyses of patient samples. In addition to metabolic markers of a patient's phenotype, metabolomics can provide markers of drug efficacy, toxicity and clearance.
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