Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Progression02:07

Tumor Progression

7.5K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.5K
Gene Therapy00:59

Gene Therapy

27.7K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.7K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

4.9K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
4.9K
Group Therapy01:26

Group Therapy

459
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
459
Behavior Therapy01:22

Behavior Therapy

732
Behavior therapy incorporates diverse techniques rooted in classical conditioning principles to address maladaptive behaviors and anxiety disorders. These methods aim to reduce avoidance behaviors, foster adaptive coping mechanisms, and alter associations between stimuli and responses, making them effective in a wide range of therapeutic contexts.
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
732
Drug Therapy01:28

Drug Therapy

304
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
304

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A subunit vaccine for multiple respiratory viruses.

Science advances·2026
Same author

SLC39A1 sustains mitochondrial integrity in alveolar epithelium during acute lung injury.

Experimental cell research·2026
Same author

Noninvasive whole-brain imaging of glymphatic dynamics.

Science advances·2026
Same author

Restoring BECN1-mediated autophagy mitigates acute lung injury caused by zinc oxide nanoparticles.

Free radical biology & medicine·2026
Same author

Myeloid-specific Becn1 deficiency elicits spontaneous pulmonary injury and exacerbates acute lung injury.

Respiratory research·2026
Same author

Immunogenicity of <i>Theileria parva</i> p67C Antigen Delivered via Adjuvanted CoPoP Liposomes in Cattle and Mice.

Vaccines·2026

Related Experiment Video

Updated: Feb 10, 2026

An In Vitro Approach to Photodynamic Therapy
04:53

An In Vitro Approach to Photodynamic Therapy

Published on: August 17, 2018

9.4K

Recent Progress in Upconversion Photodynamic Therapy.

Hailong Qiu1, Meiling Tan2, Tymish Y Ohulchanskyy3

  • 1College of Functional Crystals, Tianjin University of Technology, 300384 Tianjin, China. qiu@tjut.edu.cn.

Nanomaterials (Basel, Switzerland)
|May 23, 2018
PubMed
Summary
This summary is machine-generated.

Upconversion nanoparticles (UCNPs) enhance photodynamic therapy (PDT) by converting near-infrared light to activate photosensitizers. This nanotechnology enables deeper tissue penetration and drug delivery for improved cancer treatment.

Keywords:
cancersphotodynamic therapyupconversion nanoparticles

More Related Videos

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
08:03

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles

Published on: December 1, 2016

9.5K
Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
08:04

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro

Published on: March 18, 2014

13.2K

Related Experiment Videos

Last Updated: Feb 10, 2026

An In Vitro Approach to Photodynamic Therapy
04:53

An In Vitro Approach to Photodynamic Therapy

Published on: August 17, 2018

9.4K
Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
08:03

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles

Published on: December 1, 2016

9.5K
Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
08:04

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro

Published on: March 18, 2014

13.2K

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Photochemistry

Background:

  • Photodynamic therapy (PDT) is a cancer treatment using photosensitizers, light, and oxygen.
  • Nanotechnology offers potential improvements for PDT efficacy.
  • Upconversion nanoparticles (UCNPs) possess unique photon-converting properties.

Purpose of the Study:

  • To review recent advancements in UCNP development for PDT applications.
  • To highlight the benefits of UCNPs in enhancing PDT performance.
  • To discuss the potential of UCNPs in cancer therapy.

Main Methods:

  • Review of scientific literature on UCNPs and PDT.
  • Analysis of UCNP properties, including photon upconversion.
  • Evaluation of UCNP integration with photosensitizers and drug delivery systems.

Main Results:

  • UCNPs convert near-infrared (NIR) light to visible/UV light, activating photosensitizers.
  • NIR light penetration is deeper, enabling treatment of deeper tissues.
  • UCNPs facilitate drug loading, targeting, and controlled release.

Conclusions:

  • UCNPs represent a promising nanotechnology for advancing PDT.
  • UCNP-enhanced PDT offers improved light penetration and therapeutic potential.
  • Further development of UCNPs can broaden their application in cancer treatment.