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Effect of exhaustive exercise on liver mitochondrial function in the rat
J W Bielecki1, E Pawlicka, J Górski
1Department of Physiology, School of Medicine, Białystok.
Acta Physiologica Polonica
|September 1, 1988
Abstract:
The oxidative and phosphorylative function of rat liver mitochondria after exhaustive exercise was investigated. The stimulation of state 4 respiration (without ADP) with NADH and FADH2 dependent substrates was demonstrated. The reduction in RCR ratio (the rate of oxidation in state 3/the rate of oxidation in state 4) and enhanced activity of oligomycin sensitive ATP-ase was also found. The results suggest an inhibition of liver mitochondrial phosphorylative activity in rats exercised till exhaustion.