Related Experiment Video
Updated: Feb 10, 2026

09:33
Monitoring Conformational Dynamics of Single Unmodified Proteins using Plasmonic Nanotweezers
Published on: March 21, 2025
1.5K
Opto-thermoelectric nanotweezers
Linhan Lin1,2, Mingsong Wang1, Xiaolei Peng2
1Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX 78712, USA.
Nature Photonics
|May 23, 2018
Summary
Researchers developed opto-thermoelectric nanotweezers (OTENT) to manipulate nanoparticles using low-power optical heating. This technique converts heat loss into a directed thermoelectric field for precise control of various nanoparticles.
Area of Science:
- Nanophotonics
- Colloid Science
- Materials Science
Background:
- Optical manipulation of plasmonic nanoparticles is key for nanophotonics innovation.
- Optical heating in metal nanoparticles is typically an intrinsic loss, limiting applications.
Purpose of the Study:
- To develop a low-power optical tweezing technique by utilizing optical heating as an advantage.
- To demonstrate precise manipulation of diverse metal nanoparticles using a novel method.
Main Methods:
- Developed opto-thermoelectric nanotweezers (OTENT) using a thermoplasmonic substrate and low-power laser heating.
- Generated a light-directed thermoelectric field via spatial ion separation within the laser spot.
- Combined OTENT with dark-field optical imaging for in-situ nanoparticle trapping and spectroscopic analysis.
Main Results:
- Successfully manipulated metal nanoparticles of various materials, sizes, and shapes with single-particle resolution.
- Demonstrated selective trapping and in-situ spectroscopic resolution of nanoparticles.
- OTENT operates with simple optics, low power, and tuneable wavelengths.
Conclusions:
- Optical heating, previously a drawback, can be harnessed for nanoparticle manipulation.
- OTENT offers a versatile, low-power solution for precise control of diverse nanoparticles.
- This technique is poised to become a valuable tool in colloid science and nanotechnology.

