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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Goal-Striving Stress Is Associated with Chronic Kidney Disease Among Participants in the Jackson Heart Study
Loretta R Cain1, LáShauntá Glover2, Bessie Young3,4
1Department of Data Science, University of Mississippi Medical Center, Jackson, MS, USA. lcain@umc.edu.
Insights
High goal-striving stress is linked to a 52% increased odds of prevalent chronic kidney disease (CKD) in African Americans. This highlights the importance of addressing psychosocial factors in CKD prevention for this population.
Area of Science:
- Nephrology
- Psychosocial Epidemiology
- Public Health
Background:
- Research on psychosocial factors and chronic kidney disease (CKD) in African Americans (AAs) is limited.
- Goal-striving stress (GSS), the stress from unmet goals, is a potential psychosocial factor.
- Understanding GSS's impact on CKD is crucial for targeted interventions.
Purpose of the Study:
- To investigate the association between goal-striving stress (GSS) and prevalent chronic kidney disease (CKD).
- To examine this relationship within the African American population using the Jackson Heart Study (JHS) cohort.
Main Methods:
- Cross-sectional analysis of JHS exam 1 data from 4967 African American participants (aged 35-84).
- Logistic regression was used to evaluate the relationship between GSS levels (low, moderate, high) and CKD (eGFR < 60 mL/min/1.73m²).
- Models were adjusted for demographic, socioeconomic, health behavior, and risk factor variables.
Main Results:
- After full adjustment, high GSS was associated with a 52% increased odds of prevalent CKD (OR 1.52; 95% CI 1.04, 2.24) compared to low GSS.
- This indicates a significant link between the stress of unmet goals and the presence of kidney disease.
Conclusions:
- Discrepancies between goal aspiration and achievement are associated with prevalent CKD in African Americans.
- Future interventions for CKD prevention should consider the role of GSS.
- Addressing psychosocial stressors like GSS may be a novel approach to mitigating CKD risk.
Objective:
Research that assesses the relationship between psychosocial factors and chronic kidney disease (CKD) among African Americans (AAs) is limited. Using the Jackson Heart Study (JHS) cohort data, we investigated the association of goal-striving stress (GSS)-the stress experienced from not reaching goals-with prevalent CKD among AAs.
Design:
This was a cross-sectional analysis of JHS exam 1 data that assessed the relationship between GSS and CKD.
Setting And Participants:
We utilized a sample from the JHS (n = 4967), an AA sample of women and men, 35-84 years old from the Jackson, MS metro area.
Main Outcome Measures:
The baseline relationship between GSS levels (low, moderate, and high) and CKD (eGFR < 60 mL/min/1.73m2) was evaluated using a logistic regression model to estimate odds ratios (OR) on a 95% confidence interval (CI). The final model was adjusted for sex, age, socioeconomic status, health behaviors, risk factors, and total stress.
Results:
After full adjustment, the odds of prevalent CKD increased by 52% (OR 1.52; 95% CI 1.04, 2.24) for those reporting high (versus low) GSS.
Conclusions:
Deficiencies between goal aspiration and achievement were associated with prevalent CKD. Potential interventions might consider the impact GSS contributes to prevalent CKD.
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