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Updated: Feb 10, 2026

11:18
Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
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[Renal Infarction: multicentric cases in Piedmont]
Daria Motta1, Andrea Airoldi2, Serena Bainotti3
1S.C. Nefrologia e Dialisi, Martini Torino.
Summary
Renal infarction diagnosis is often delayed, impacting treatment. Key symptoms include fever, hypertension, and pain, with elevated LDH and CRP common laboratory findings.
Area of Science:
- Nephrology
- Radiology
- Internal Medicine
Background:
- Renal infarction is a rare condition with varied presentations.
- Early diagnosis and treatment are crucial for preserving kidney function.
Purpose of the Study:
- To analyze clinical, instrumental, and laboratory features of renal infarction.
- To evaluate diagnostic and therapeutic strategies for renal infarction.
Main Methods:
- An observational, polycentric review of 48 renal infarction cases diagnosed via Computed Tomography Angiography (CTA) between 2013-2015.
- Cases were categorized by etiology: cardio-embolic, coagulation abnormalities, or other/idiopathic.
Main Results:
- The median time from symptom onset to diagnosis was 2 days.
- Common symptoms included fever (67%), hypertension (58%), and pain (54%).
- Elevated lactate dehydrogenase (LDH) and C-reactive protein (CRP) were observed in 96% and 94% of cases, respectively. Cardio-embolic cases were older, while coagulation abnormalities and idiopathic cases showed higher rates of smoking.
Conclusions:
- Despite characteristic features, a significant diagnostic delay persists.
- Timely diagnosis is essential for effective therapeutic intervention in renal infarction.
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