Prediction of mortality in pediatric traumatic brain injury: Implementations from a tertiary pediatric intensive care
Ebru Atike Ongun1, Oğuz Dursun
1Department of Pediatric Critical Care, Akdeniz University Faculty of Medicine, Antalya-Turkey. ebruongun@akdeniz.edu.tr.
Insights
Traumatic brain injury (TBI) in children admitted to the pediatric intensive care unit has a 12.5% mortality rate. The Rotterdam-CT score is an independent risk factor for mortality in pediatric TBI.
Area of Science:
- Pediatric intensive care
- Neurotrauma
- Critical care medicine
Background:
- Traumatic brain injury (TBI) is a significant cause of mortality in children.
- Identifying risk factors for TBI mortality in pediatric intensive care units (PICUs) is crucial for improving patient outcomes.
Purpose of the Study:
- To investigate the mortality risk factors associated with traumatic brain injury in pediatric intensive care unit admissions.
- To identify predictors of mortality in pediatric TBI patients.
Main Methods:
- Analysis of 88 pediatric patients admitted to the PICU with TBI between September 2014 and December 2016.
- Data collected included Glasgow Coma Scale, emergency department and ICU course, treatment strategies, axonal injury, intubation/tracheostomy rates, length of stay, Rotterdam-CT scores, Injury Severity Score (ISS), and Pediatric Risk of Mortality (PRISM-III) scores.
Main Results:
- Older age was associated with trauma severity (p=0.010).
- Axonal injury correlated with prolonged intubation, ICU, and hospital stay (p<0.001).
- Six children required tracheostomy, with five decannulated within 6 months.
Conclusions:
- The overall mortality rate was 12.5%, with six patients progressing to brain death.
- Initial hypotension, lung contusion, ISS, and Rotterdam-CT scores were associated with mortality.
- The Rotterdam-CT score emerged as an independent risk factor for mortality, increasing the odds of recovery by 20.334 times (95% CI 1.999-206.879).
Background:
To explore the mortality risk factors of traumatic brain injury in pediatric intensive care unit admissions.
Methods:
Eighty-eight children (categorized using the Glasgow Coma Scale) between September 2014 and December 2016 were analyzed. Emergency department and intensive care course, treatment strategies, axonal injury, intubation and tracheostomy rates, length of intensive care and hospitalization, Rotterdam-CT scores, injury severity scores, and PRISM-III scores were recorded.
Results:
Older age was associated with trauma severity (p=0.010). Target serum osmolality was reached at 8.5 (3.5-40) hours in patients undergoing anti-edema therapy. ICP-monitoring rates was 8%; in absence of ICP-monitorization clinical follow-up was performed through repeated brain tomographies. Axonal injury was associated with prolonged intubation, intensive care and hospital stay (p<0.001, p<0.001, p=0.030). Six children required tracheostomy at 14.33±1.03 days; decannulations were performed within 6 months in five children.
Conclusion:
Mortality rate was 12.5%; six patients progressed to brain death with organ donor approvals in five. Initial hypotension, lung contusion, injury severity scores and Rotterdam-CT scores were related with mortality. Rotterdam-CT score was determined as the independent risk factor for mortality; one increment in the score increased the odd of recovery by 20.334 times (%95 CI 1.999-206.879). ISS score was also borderline significant (p=0.052; OR:1.195 %95 CI 0.999-1.430).
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