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Updated: Feb 10, 2026

A Fluorescence-based Assay of Phospholipid Scramblase Activity
Published on: September 20, 2016
CCTα Commands Phospholipid Homeostasis from the Nucleus
Rosemary Cornell1, Bruno Antonny2
1Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A-1S6, Canada.
Abstract:
Enzyme control by their products facilitates cellular homeostasis, but for phospholipids, feedback mechanisms also arise from changes in membrane physical properties. In this issue of Developmental Cell, Haider et al. (2018) show that in many actively growing cells, an enzyme of phosphatidylcholine synthesis senses lipid packing in the nuclear membrane.
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