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Related Experiment Video

Updated: Feb 10, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Visual analogue scales for interstitial lung disease: a prospective validation study.

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Summary

Visual analogue scales (VAS) effectively assess dyspnoea and fatigue in interstitial lung disease (ILD). The minimal clinically important difference (MCID) is established, aiding non-specialist monitoring of ILD progression.

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Area of Science:

  • Pulmonary Medicine
  • Clinical Assessment Tools
  • Interstitial Lung Disease (ILD)

Background:

  • Visual analogue scales (VAS) are widely used for symptom assessment but lack validation in interstitial lung disease (ILD).
  • Simple, validated tools are needed for non-specialist clinicians to monitor ILD disease burden.
  • Assessing ILD progression and treatment response requires reliable symptom measurement.

Purpose of the Study:

  • To validate VAS for assessing changes in dyspnoea, cough, and fatigue in ILD patients.
  • To establish the minimal clinically important difference (MCID) for these VAS symptom assessments.
  • To provide a tool for remote ILD patient monitoring.

Main Methods:

  • 64 ILD patients completed VAS for dyspnoea, cough, and fatigue at baseline and 3-6 months.
  • Baseline assessments included King's Brief ILD questionnaire (K-BILD), lung function, and 6-minute walk test (6MWT).
  • MCID was determined by analyzing VAS change in patients reporting a 'small but just worthwhile' symptom improvement, validated in a separate cohort.

Main Results:

  • VAS demonstrated significant differences between patients reporting symptom change versus no change (P < 0.01).
  • MCID estimates: 22.0 mm for VAS Dyspnoea and 14.5 mm for VAS Fatigue.
  • VAS Dyspnoea changes correlated significantly with K-BILD, forced vital capacity, and 6MWT, but VAS Cough did not reach significance.

Conclusions:

  • VAS is a valid tool for tracking dyspnoea and fatigue changes in ILD patients.
  • Established MCID values (22.0 mm for dyspnoea, 14.5 mm for fatigue) provide benchmarks for clinical significance.
  • Validated VAS can support ILD management outside specialist centers.