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Initial development of an evidence base for personalized medicine's translation to clinical practice and health
Kathryn A Phillips1, Stephanie L Van Bebber1,2, Amalia M Issa3
1University of California, Department of Clinical Pharmacy, School of Pharmacy, San Francisco, 3333 California St Suite 420 Box 0613, University of California, San Francisco, CA 94143-0613, USA. PhillipsK@pharmacy.ucsf.edu.
Abstract:
A major challenge to adoption of personalized medicine approaches, such as pharmacogenomics, is that data to address many critical questions relevant to clinical application, economics, policy and regulation are typically unavailable or widely dispersed. The evidence base we tentatively call Evaluation Data for Assessing Personalized Medicine Translation (EDAPT) would generate the foundation for a database of information. This article begins with a description of the rationale and conceptual framework for this effort.