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Papillary glioneuronal tumor. A case report
Julián Castro Castro1, Olalla Lista Martínez1, Nuria Caramés Díaz2
1Servicio de Neurocirugía, Complexo Hospitalario Universitario de Ourense, Ourense, España.
Insights
Papillary glioneuronal tumor (PGNT) is a rare, low-grade brain tumor. This case report details a 13-year-old boy
Area of Science:
- Neuro-oncology
- Neuropathology
Background:
- Papillary glioneuronal tumor (PGNT) is a rare, WHO Grade I central nervous system neoplasm.
- Typically affects juvenile and young adult patients, often presenting with seizures or headaches.
Observation:
- A 13-year-old boy presented with a right temporo-occipital lesion after a head injury.
- CT and MRI scans revealed a lesion suggestive of a primary brain tumor.
Findings:
- Surgical resection was performed, leading to an uneventful recovery.
- Pathological analysis confirmed the characteristic pseudopapillary structure of PGNT, with both glial and neuronal components.
Implications:
- This case highlights the clinical, radiological, and histological features of PGNT.
- Contributes to understanding this infrequent but distinct type of brain tumor.
Abstract:
Papillary glioneuronal tumor (PGNT) is a recently described central nervous system neoplasm. In 2007, the World Health Organization classified this tumor as a grade I neuronal-glial neoplasm. Patients are usually juvenile and young adults who commonly present with headache or seizures. We report a case of a 13-year-old boy that was related to our hospital after suffering a mild head injury result of an automobile accident. Emergent CT scan showed a right hypointense temporo-occipital lesion. MRI confirmed the presence of a lesion suggestive of a primary brain tumor. The patient underwent total resection of the tumor, followed by an uneventful recovery. Pathological analysis of the lesion revealed characteristic pseudopapillary structure with astrocytes and neurons, compatible with PGNT. We discuss the clinical, Radiological and histological features of this infrequent type of tumors.
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