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Co-Morbidities as Predictors of Airflow Limitation among Smokers in England
Reem Kayyali1, Yusur Hassan2, Iman Hesso3
1School of Life Sciences, Pharmacy and Chemistry, Kingston University London, Penrhyn Road, Kingston Upon Thames KT1 2EE, UK. R.Kayyali@kingston.ac.uk.
Abstract:
The prevalence of co-morbidities among patients with Chronic Obstructive Pulmonary Disease (COPD) is well documented in the literature. Therefore, this pilot study aimed to identify whether co-morbidities screening would enhance COPD case-finding. Smoking patients were approached at Croydon University Hospital and two local community pharmacies (CPs). Their co-morbidities, respiratory symptoms, smoking pack-years and exercise capacity were collected. Airflow limitation was determined using handheld spirometry (COPD-6) device. The prevalence of airflow limitation was 42% (n = 21/50). The main identified predictors of airflow limitation were: co-morbidities (OR = 9, CI: 1.04⁻77.81, p = 0.025), respiratory symptoms (OR = 33.54, CI: 1.06⁻11.77, p = 0.039) and smoking history of ≥20 pack-years (OR = 3.94, CI: 1.13⁻13.64, p = 0.029). CPs were the main location for case-finding. This study demonstrated the need to screen for co-morbidities for COPD case-finding within CPs.
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