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Updated: Feb 10, 2026

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System
Published on: January 12, 2017
Serum Cystatin C Level Is Not a Promising Biomarker for Predicting Clinicopathological Characteristics of Bladder
Hui Wang1,2, Lijian Gao1,2, Cuiyu Meng3
1Department of Urology, Qilu Hospital of Shandong University, Jinan 250012, China.
Abstract:
The role of cystatin C (Cys-C) in tumorigenesis and progression of bladder urothelial tumors (BUT) is still indefinite. We retrospectively collected the clinical information from the records of 425 BUT patients. Pretreatment serum Cys-C levels were compared across the various groups. Then we subgroup the patients with GFR ≥ 90 mg/min/1.73 m2, to exclude the effects of lower renal function on cystatin C. No statistically significant differences in the levels of serum Cys-C were found among the tumor characteristics (all P > 0.05). In conclusion, circulating Cys-C was not a reliable predictor for clinicopathological characteristics of BUT patients.
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