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Updated: Feb 10, 2026

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Fast 3-T MR-guided transrectal prostate biopsy using an in-room tablet device for needle guide alignment: a
Christiaan G Overduin1, Jan Heidkamp2, Eva Rothgang3
1Department of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101 (767), 6500 HB, Nijmegen, The Netherlands. kristian.overduin@radboudumc.nl.
An in-room tablet device is feasible and safe for guiding needle alignment during magnetic resonance (MR)-guided prostate biopsies. This method successfully targeted cancer-suspicious regions, potentially reducing procedure times.
Area of Science:
- Medical Imaging
- Urology
- Interventional Radiology
Background:
- Magnetic resonance (MR)-guided transrectal prostate biopsy is an evolving technique for cancer detection.
- Accurate needle-guide alignment is crucial for targeting cancer-suspicious regions (CSRs).
- Traditional methods may involve complex adjustments and longer procedure times.
Purpose of the Study:
- To evaluate the feasibility and safety of using an in-room tablet device for needle-guide alignment in MR-guided prostate biopsies.
- To assess the accuracy and efficiency of targeting CSRs with this new approach.
Main Methods:
- Twenty patients with PI-RADS score ≥ 4 CSRs underwent MR-guided biopsy.
- An MR fluoroscopy sequence provided real-time feedback on an in-room tablet.
- Needle-guide alignment was performed using the tablet interface for targeting.
Main Results:
- Technical success for needle-guide alignment was achieved in all patients (100%).
- Targeting and sampling of CSRs (median size 14 mm) were successful in 95% after a single alignment step.
- No per-procedural or post-biopsy complications were reported.
- Mean time to first biopsy was 5.8 minutes; mean total procedure time was 23.7 minutes.
Conclusions:
- In-room tablet-assisted needle-guide alignment is a feasible and safe technique for MR-guided prostate biopsy.
- This method allows for precise targeting of CSRs, with high success rates after single alignment.
- The use of the tablet device shows potential for reducing overall procedure time.
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