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Updated: Feb 10, 2026

Mouse Models for Graft Arteriosclerosis
Published on: May 14, 2013
Rationalizing the path to a universal graft recipient
1Conceptual Immunology Group, The Salk Institute, 10010 N. Torrey Pines Rd., La Jolla, CA, 92037, USA. cohn@salk.edu.
Abstract:
The goal of this essay is to take the reader through the logic that would predict universal graft acceptance. The story begins with what we learned from an experiment performed 65 years ago and develops that information in greater depth. The pathway of the analysis leads to the conclusion that controlling the immune system at the level of the T-helper would be the best way to approach a general solution to the problem of graft acceptance.
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