Related Experiment Video
Updated: Feb 10, 2026

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention
Published on: September 11, 2017
Attentional modulation of desensitization to odor
Nicholas Fallon1, Timo Giesbrecht2, Andrej Stancak3
1Department of Psychological Sciences, Institute of Psychology, Health, and Society, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool, L69 7ZA, UK. nickfal@liverpool.ac.uk.
Attention significantly impacts how quickly we stop smelling an odor. Distracted attention accelerates odor desensitization, while focused attention reveals regular sensitivity patterns.
Area of Science:
- Neuroscience
- Sensory Perception
- Olfactory Research
Background:
- Olfactory responsiveness decreases with prolonged odor exposure.
- Mechanisms of olfactory desensitization are not fully understood.
- Central-cognitive processes may modulate olfactory desensitization.
Purpose of the Study:
- Investigate the effect of attention on perceived odor intensity.
- Examine how attentional focus influences olfactory desensitization.
- Determine the role of top-down control in odor perception.
Main Methods:
- Within-subjects design with 19 participants.
- 10-minute odor exposure with continuous intensity ratings.
- Auditory oddball task to manipulate attentional focus (distraction vs. focused odor rating).
Main Results:
- Distraction led to significantly lower intensity ratings in specific time windows.
- Desensitization followed a linear function with focused attention versus exponential decay with distraction.
- Focused attention revealed regular odor sensitivity patterns (1-2 minute intervals).
- Augmented low-frequency oscillation spectral power observed during focused attention.
Conclusions:
- Attentional factors demonstrably modulate olfactory desensitization.
- Distracted attention accelerates initial odor desensitization.
- Top-down cognitive control is relevant for ongoing odor perception.
Related Concept Videos
GPCR Desensitization
Desensitization and Tachyphylaxis
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
Physical and Chemical Properties of Matter
Measurement: Derived Units

