Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A re-evaluation of corneal development.

D Sevel1, R Isaacs

  • 1Division of Ophthalmology, Scripps Clinic and Research Foundation, La Jolla, California.

Transactions of the American Ophthalmological Society
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Crop production in the USA is frequently limited by a lack of pollinators.

Proceedings. Biological sciences·2020
Same author

Bevacizumab as adjuvant treatment of colon cancer: updated results from the S-AVANT phase III study by the GERCOR Group.

Annals of oncology : official journal of the European Society for Medical Oncology·2020
Same author

Narrow pollen diets are associated with declining Midwestern bumble bee species.

Ecology·2019
Same author

Design errors in vital sign charts used in consultant-led maternity units in the United Kingdom.

International journal of obstetric anesthesia·2019
Same author

Limited phenological and dietary overlap between bee communities in spring flowering crops and herbaceous enhancements.

Ecological applications : a publication of the Ecological Society of America·2018
Same author

Evaluation of Nasonov Pheromone Dispensers for Pollinator Attraction in Apple, Blueberry, and Cherry.

Journal of economic entomology·2018
Same journal

The Utility of Color Duplex Ultrasonography in the Diagnosis of Giant Cell Arteritis: A Prospective, Masked Study. (An American Ophthalmological Society Thesis).

Transactions of the American Ophthalmological Society·2018
Same journal

Autoimmune Retinopathy: Current Concepts and Practices (An American Ophthalmological Society Thesis).

Transactions of the American Ophthalmological Society·2018
Same journal

Erratum: Predictors of Intraocular Pressure After Phacoemulsification in Primary Open-Angle Glaucoma Eyes with Wide Versus Narrower Angles (An American Ophthalmological Society Thesis).

Transactions of the American Ophthalmological Society·2018
Same journal

The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis).

Transactions of the American Ophthalmological Society·2018
Same journal

The Effects of Phacoemulsification and Intraocular Lens Implantation on Anatomical and Functional Parameters in Patients with Primary Angle Closure: A Prospective Study. (An American Ophthalmological Society Thesis).

Transactions of the American Ophthalmological Society·2017
Same journal

Predictors of Intraocular Pressure After Phacoemulsification in Primary Open-Angle Glaucoma Eyes with Wide Versus Narrower Angles (An American Ophthalmological Society Thesis).

Transactions of the American Ophthalmological Society·2017
See all related articles

This study details the developmental origins of the cornea, including its epithelium, stroma, and membranes. It explains how the cornea forms and changes shape during embryonic development, influenced by the lens and aqueous humor dynamics.

Area of Science:

  • Ophthalmology
  • Developmental Biology
  • Histology

Background:

  • The cornea's developmental origins have been debated, particularly regarding the sources of its stromal and epithelial layers.
  • Understanding corneal development is crucial for addressing congenital corneal abnormalities.

Purpose of the Study:

  • To elucidate the embryonic origins and developmental processes of the corneal layers and structures.
  • To clarify the roles of the lens, tunica vasculosa lentis, and aqueous humor in corneal morphogenesis.

Main Methods:

  • Histological examination of developing ocular tissues.
  • Comparative analysis of corneal development across different stages.

Main Results:

  • The corneal epithelium originates from surface ectoderm and superficial corneal stroma cells.

Related Experiment Videos

  • Bowman's and Descemet's membranes arise from mesenchymal cell processes within the corneal stroma.
  • Corneal thinning is attributed to lens impingement, while stromal development occurs in situ.
  • Aqueous humor production and drainage systems develop concurrently with the regression of the tunica vasculosa lentis, influencing corneal shape.

    • Conclusions:

    • The cornea's distinct layers and structures have specific mesenchymal and ectodermal origins.
    • Intraocular pressure and fluid dynamics play a significant role in shaping the developing cornea.
    • The limbus serves as a critical stabilizing site during corneal enlargement.