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Noninvasive, High-throughput Determination of Sleep Duration in Rodents
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Sleep duration and mortality - Does weekend sleep matter?

Torbjörn Åkerstedt1,2, Francesca Ghilotti3,4, Alessandra Grotta5,6

  • 1Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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|May 24, 2018
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Short weekend sleep increases mortality risk in adults under 65. Consistently sleeping too little or too much, on weekdays or weekends, also elevates mortality risk in this age group.

Keywords:
agingcompensationlongrestedshortweekdayweekend

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Area of Science:

  • Epidemiology
  • Sleep Medicine
  • Public Health

Background:

  • Previous research indicates a U-shaped link between weekday sleep duration and mortality.
  • The impact of weekend sleep duration on overall mortality remains less understood.

Purpose of the Study:

  • To investigate the association between weekday and weekend sleep durations with all-cause mortality.
  • To examine age-specific effects on the sleep-mortality relationship.

Main Methods:

  • A large cohort of 43,880 subjects was followed for 13 years.
  • Cox proportional hazards regression models were used to analyze mortality risk.
  • Stratified analyses were performed for age groups (<65 and ≥65 years).

Main Results:

  • In individuals <65 years, short weekend sleep (≤5 hours) was linked to a 52% higher mortality rate.
  • Consistently sleeping ≤5 hours or ≥8 hours daily was associated with increased mortality in those <65 years.
  • No significant associations were found between weekend sleep duration and mortality in individuals ≥65 years.

Conclusions:

  • Short weekend sleep is a risk factor for increased mortality in adults under 65.
  • Consistent short or long sleep durations on both weekdays and weekends elevate mortality risk in younger adults.
  • Longer weekend sleep may potentially mitigate risks associated with shorter weekday sleep in younger individuals.