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Human excimer laser corneal surgery: preliminary report
Transactions of the American Ophthalmological Society
|January 1, 1988
Summary
The first human trial of the 193 nm argon fluoride excimer laser for superficial keratectomy shows promise for future reconstructive and refractive keratoplasty. Further research is needed on corneal wound healing and long-term stability after laser ablation.
Area of Science:
- Ophthalmology
- Laser Surgery
- Corneal Surgery
Background:
- The argon fluoride excimer laser at 193 nm is being investigated for superficial keratectomy.
- This study describes the first human trial of this technique.
Observation:
- Ten human eyes underwent superficial keratectomy using the excimer laser.
- Histopathological evaluation was performed on four eyes, and gross appearance was assessed for six eyes up to 10 months post-treatment.
Findings:
- The excimer laser superficial keratectomy procedure shows potential for future reconstructive and refractive keratoplasty.
- The study highlights the need for extensive investigation into corneal wound healing and the long-term stability of laser-induced refractive corrections.
Implications:
- Optimal laser parameters for refractive corrections and corneal surgical techniques require establishment.
- Critical analysis of pathophysiological and histopathological changes from excimer laser-corneal tissue interaction is essential.