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Mesh Analysis01:20

Mesh Analysis

1.5K
Mesh analysis is a valuable method for simplifying circuit analysis using mesh currents as key circuit variables. Unlike nodal analysis, which focuses on determining unknown voltages, mesh analysis applies Kirchhoff's voltage law (KVL) to find unknown currents within a circuit. This method is particularly convenient in reducing the number of simultaneous equations that need to be solved.
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
1.5K
Mesh Analysis with Current Sources01:10

Mesh Analysis with Current Sources

2.0K
Mesh analysis becomes simpler when analyzing circuits with current sources, whether independent or dependent. The presence of current sources reduces the number of equations required for analysis. Two cases illustrate this:
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
2.0K
Mesh Analysis for AC Circuits01:12

Mesh Analysis for AC Circuits

714
In the domain of radio communication, the significance of impedance matching must be considered. It is crucial to ensure the efficient transmission of signals between radio transmitters and receivers. Achieving this balance involves using impedance-matching circuits, with one fundamental configuration comprising a resistor, capacitor, and inductor.
The process of harmonizing these impedances begins with a clear understanding of the input and output signals. Once these signals are known, the...
714
Long-term Depression01:05

Long-term Depression

33.3K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.3K
Long-term Depression01:03

Long-term Depression

3.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.4K
Long-term Potentiation01:35

Long-term Potentiation

58.7K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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Related Experiment Video

Updated: Feb 10, 2026

Transvaginal Mesh Insertion in the Ovine Model
10:32

Transvaginal Mesh Insertion in the Ovine Model

Published on: July 27, 2017

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Using meshes for MeSH term enrichment and semantic analyses.

Guangchuang Yu1,2

  • 1Institute of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

Bioinformatics (Oxford, England)
|May 24, 2018
PubMed
Summary

The meshes R package enhances life science research by measuring semantic similarity between Medical Subject Headings (MeSH) terms and gene products. It aids in knowledge mining and biological meaning extraction across many species.

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Last Updated: Feb 10, 2026

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Life Sciences

Background:

  • Medical Subject Headings (MeSH) is the National Library of Medicine (NLM) controlled vocabulary for indexing articles in MEDLINE/PubMed.
  • MeSH provides comprehensive annotations crucial for life science research and knowledge discovery.

Purpose of the Study:

  • To introduce the meshes R package for semantic similarity analysis of MeSH terms and gene products.
  • To facilitate knowledge mining and biological interpretation using MeSH annotations.
  • To support enrichment analysis for gene lists, expression profiles, and genomic regions.

Main Methods:

  • The meshes package calculates semantic similarity between MeSH terms and gene products.
  • It performs enrichment analysis utilizing MeSH annotations.
  • The package supports over 70 species and offers visualization tools.

Main Results:

  • The meshes package enables semantic similarity measurement for enhanced knowledge mining.
  • It provides tools for extracting biological meanings from diverse biological data.
  • High-quality visualizations aid in the interpretation of analysis results.

Conclusions:

  • The meshes package is a valuable tool for leveraging MeSH annotations in life science research.
  • It facilitates deeper biological insights through semantic similarity and enrichment analysis.
  • The package's broad species support and visualization capabilities enhance its utility.