Related Experiment Video
Updated: Feb 10, 2026

Generation and Characterization of Rat Uterus Organoids from Rat Endometrial Epithelial Stem Cells
Published on: August 2, 2024
Comparison of the Thermal Spread of Three Different Electrosurgical Generators on Rat Uterus: A Preliminary
Tolga Karacan1, Taner Usta2, Aysel Ozkaynak2
1Department of Obstetrics and Gynecology, University of Health Sciences, Bagcilar Training and Research Hospital, Istanbul, Turkey.
Background/Aims:
The objective of this study was to compare the depth and width of thermal spread caused on rat uterine tissue after application of 3 different electrosurgical generators.
Methods:
Alsa Excell 350 MCDSe (Unit A), Meditom DT-400P (Unit M), and ERBE Erbotom VIO 300 D (Unit E) electrosurgical units (ESUs) were used. The number of Wistar Hannover rats required to obtain valid results was 10. The primary objective of the study was to compare the 3 ESUs using the same instrument and the same waveform. The secondary objective of the study was to compare the differences between monopolar and bipolar systems of each ESU separately using the same waveform.
Results:
The thermal spread caused by each ESU using monopolar instruments with continuous and interrupted waveforms was significantly different. Among the 3 devices, Unit A caused the largest thermal uterine tissue spread. On the other hand, Unit E caused the most superficial thermal tissue spread, and the smallest thermal spread among all ESUs.
Conclusions:
Surgeons should note that different ESUs used with the same power output might create different thermal effects especially in the monopolar configuration within the same waveform, for the same duration, and with the same instrument.
Related Concept Videos
Histology of the Uterus
The endometrium is the...
Uterus and Cervix
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs...
Spreading of Chromatin Modifications
Writers
The writer...
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Thermal expansion and Thermal stress: Problem Solving
To solve the problem, first, identify the known and unknown quantities. The initial length (L) of the bridge is 1275 m, the coefficient of linear expansion (α) for steel is 12 x 10-6/°C, and the change in temperature (ΔT) is 55...
Thermal Strain

