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Published on: January 18, 2018
[Management of Acute Cholecystitis]
1Department of Internal Medicine, Biomedical Research Institute, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.
Insights
Acute cholecystitis, a severe gallstone complication, has a 3% mortality rate, increasing with patient age and comorbidities. Early laparoscopic cholecystectomy is standard, but drainage offers an alternative for high-risk patients.
Area of Science:
- Gastroenterology
- Surgical Oncology
Background:
- Acute cholecystitis is a serious complication of gallstones.
- Mortality is approximately 3%, rising with patient age and comorbidities.
- Delayed treatment can lead to grave complications.
Purpose of the Study:
- To review the management of acute cholecystitis.
- To discuss treatment options based on patient risk.
- To highlight alternatives to cholecystectomy.
Main Methods:
- Review of current treatment standards for acute cholecystitis.
- Discussion of surgical versus drainage-based approaches.
- Consideration of patient-specific factors like operational risk.
Main Results:
- Early laparoscopic cholecystectomy is the standard of care.
- Gallbladder drainage (percutaneous or endoscopic) is a viable alternative for high-risk patients.
- Gallstone removal via drainage tract may be considered for select patients.
Conclusions:
- Treatment for acute cholecystitis should be individualized based on disease severity and patient risk.
- Gallbladder drainage provides an alternative to immediate surgery.
- Definitive treatment, including cholecystectomy or gallstone removal, should be considered after recovery.
Abstract:
Acute cholecystitis is a common serious complication of gallstones. The reported mortality of acute cholecystitis is approximately 3%, but the rate increases with age or comorbidity of the patient. If appropriate treatment is delayed, complications can develop as a consequence with a grave prognosis. The current standard of care in acute cholecystitis is an early laparoscopic cholecystectomy with the appropriate administration of fluid, electrolyte, and antibiotics. On the other hand, the severity of the disease and patient's operational risk must be considered. In those with high operational risks, gall bladder drainage can be performed as an alternative. Currently percutaneous and endoscopic drainage are available and show clinical success in most cases. After recovering from acute cholecystitis, the patients who have undergone drainage should be considered for cholecystectomy as a definitive treatment. However, in elderly patients or patients with significant comorbidity, operational risks may still be high, making cholecystectomy inappropriate. In these patients, gallstone removal using the percutaneous tract or endoscopy may be considered.
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Classification
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