Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Beams01:30

Beams

1.9K
Beams are integral components of structural engineering and construction, designed to support loads applied at various points along their length. These long, straight members can be classified based on geometry, cross-section, support type, and equilibrium condition.
Based on geometry, beams can be straight, tapered, or curved. Straight beams are the most common type and have a constant cross-section throughout their length. Tapered beams, on the other hand, have a varying cross-section along...
1.9K
Work Done on a System by External Force01:11

Work Done on a System by External Force

3.0K
The work done by an external force on a particle changes its kinetic energy. However, internal forces must also be considered for a system of interacting particles. The potential energy formulation helps formulate the effect of internal forces. The net work done by an external force can be written in terms of the total change of mechanical energy, which includes both kinetic and potential energies.
In the presence of a non-conservative opposing force, like friction, some part of the work done...
3.0K
Deflection of a Beam01:19

Deflection of a Beam

740
Accurately determining beam deflection and slope under various loading conditions in structural engineering is crucial for ensuring safety and structural integrity. Singularity functions offer a streamlined approach to analyzing beams, especially when multiple loading functions complicate the bending moment equation.
Singularity functions, described in an earlier lesson, are powerful mathematical tools that represent discontinuities within a function commonly encountered in structural loading...
740
Internal and External Forces01:12

Internal and External Forces

16.3K
Newton's first law states that a net external force causes a change in motion. External forces act on an object or system, originating outside of the object or system. In contrast, internal forces originate inside the system of interest and do not lead to any acceleration. In simpler words, internal forces are forces that act on one part of an object and are exerted by another part of the same object. External forces are forces that act on an object due to some other object. Therefore, when...
16.3K
External and Internal Respiration01:24

External and Internal Respiration

7.7K
External respiration occurs in the lungs, and it is the first step in the journey of oxygen inside the body. When we inhale, oxygen enters our lungs and diffuses across the thin alveolar membrane. The alveoli are tiny, air-filled sacs that provide a vast surface area for gas exchange. Oxygen in the alveoli has a higher partial pressure (105 mmHg) than in the adjacent pulmonary capillaries (40 mmHg), establishing a pressure gradient. As a result, oxygen molecules move from the alveoli into the...
7.7K
General External Flow Characteristics01:26

General External Flow Characteristics

554
The study of external flow is essential for creating structures and objects that interact efficiently and safely with moving fluids, such as air or water. When a body is immersed in a flowing fluid, it experiences two primary forces: drag, which opposes motion along the flow direction, and lift, which acts perpendicular to the flow. The shape, size, and orientation of the object influence these forces.Streamlined and Blunt Bodies in External FlowObjects in fluid flow are classified as...
554

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamic immune profiling predicts response to radiation plus anti-PD-1 therapy in oligometastatic renal cell carcinoma.

Nature communications·2026
Same author

A Sensory Adaptation Program for Individuals With Mal de Débarquement Syndrome: A Case Series.

Journal of neurologic physical therapy : JNPT·2026
Same author

Is there an association between acute, subacute, and late genitourinary quality of life with prostate SBRT boost?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Building an Interoperable Rare Disease Multi-omic Resource: The GREGoR Data Model and Dataset.

bioRxiv : the preprint server for biology·2026
Same author

Lessons Learned From a Victorian Regional Allied Health Professional and Workforce Support Project.

The Australian journal of rural health·2026
Same author

Unusual Cause of Pain and Extensive Leg Swelling in a Teenage Girl.

Pediatrics in review·2026

Related Experiment Video

Updated: Feb 10, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

15.0K

PROstate Multicentre External beam radioTHErapy Using a Stereotactic boost: the PROMETHEUS study protocol.

Matthew Richardson1, Mark Sidhom2, Sarah Gallagher1

  • 1Calvary Mater Newcastle, Newcastle, NSW, Australia.

BMC Cancer
|May 26, 2018
PubMed
Summary
This summary is machine-generated.

The PROMETHEUS study evaluates Prostate Stereotactic Body Radiotherapy (SBRT) as a non-surgical alternative to High Dose Rate Brachytherapy (HDRB) boost for prostate cancer. It assesses safety, efficacy, and feasibility across Australian centers.

Keywords:
Dose HypofractionationPlanning techniquesProstatic neoplasmsRadiation oncologyRadiosurgery

More Related Videos

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

47.5K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.7K

Related Experiment Videos

Last Updated: Feb 10, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

15.0K
Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

47.5K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.7K

Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Clinical Trials

Background:

  • High Dose Rate Brachytherapy (HDRB) boost is a standard treatment for prostate cancer (PC).
  • The PROstate Multicentre External beam radioTHErapy Using Stereotactic boost (PROMETHEUS) study introduces non-surgical stereotactic techniques.
  • A dose escalation sub-study is included to explore advanced radiotherapy options.

Purpose of the Study:

  • To explore the safety, efficacy, and feasibility of Prostate Stereotactic Body Radiotherapy (SBRT) in multiple Australian centers.
  • To provide evidence for a non-surgical alternative to HDRB boost for prostate cancer.
  • To introduce and evaluate advanced radiotherapy techniques in Australian cancer centers.

Main Methods:

  • Patients with intermediate or high-risk prostate cancer were enrolled.
  • A SBRT boost of 19Gy in two fractions was delivered, followed by 46Gy in 23 fractions of external beam radiotherapy (EBRT).
  • Dose escalation to a maximum of 22Gy in two fractions was planned, with safety assessed via CTCAE toxicities and quality of life, and efficacy by biochemical control at 3 years.

Main Results:

  • This section is not detailed in the provided abstract.
  • Further analysis is required to determine the primary outcomes.
  • The study is registered under ACTRN12615000223538.

Conclusions:

  • The PROMETHEUS study aims to establish SBRT as a viable non-surgical alternative to HDRB boost for prostate cancer.
  • The study seeks to advance the adoption of sophisticated radiotherapy techniques in Australian oncology centers.