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Cardiac complications after stroke: protocol for a systematic review and meta-analysis

Guidelle Héloïse Kenmogne-Domning1, Joseph Kamtchum-Tatuene2,3, Steve Raoul Noumegni4

  • 1Higher Institute of Health Sciences, Universite des Montagnes, Bangangté, Cameroon.

BMJ Open
|May 26, 2018
PubMed

Insights

Cardiac complications significantly impact stroke patient mortality and disability. This systematic review synthesizes data on their incidence and fatality to guide better patient outcomes.

Area of Science:

  • Cardiology
  • Neurology
  • Public Health

Background:

  • Stroke is a leading global cause of death and disability.
  • Cardiac complications contribute significantly to stroke-related mortality, with reported rates varying widely.
  • Understanding the burden of these complications is crucial for improving patient management and outcomes.

Purpose of the Study:

  • To systematically review and summarize existing data on the prevalence, incidence, and mortality of cardiac complications following stroke.
  • To provide an up-to-date overview of the burden of cardiac complications after stroke to inform clinical practice.

Main Methods:

  • A comprehensive systematic review and meta-analysis of studies published between 1950 and 2017.
  • Inclusion of cross-sectional, case-control, cohort studies, and clinical trials involving adult and pediatric populations.
  • Data extraction and quality assessment by two independent reviewers, with heterogeneity evaluated using Cochran's Q statistic and meta-analysis performed using random-effect or fixed-effect models.

Main Results:

  • The review will synthesize data on the prevalence, incidence, and mortality rates of various cardiac complications post-stroke.
  • Meta-analysis will provide pooled estimates of these outcomes, accounting for study heterogeneity.
  • Potential for identifying trends and significant risk factors associated with cardiac complications after stroke.

Conclusions:

  • The findings will offer a consolidated understanding of the cardiac complication burden in stroke patients.
  • This knowledge is expected to enhance early recognition and management strategies for cardiac issues post-stroke.
  • Ultimately, the review aims to contribute to improved patient outcomes and reduced mortality and disability associated with stroke.
Abstract

Keywords:
cardiac complicationsepidemiologymortalitystrokesystematic review

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