Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Restorative Care01:19

Restorative Care

2.4K
Restorative care is provided once a patient has been discharged from a healthcare facility and requires additional services. The additional services include home care, rehabilitation programs, and extended care. Restorative care centers help the patient regain their previous level of functioning or acquire a new level of functioning due to the incapacitating effects of a disease or a disability. It aims to assist patients in enhancing their quality of life by encouraging independence,...
2.4K
Translesion DNA Polymerases02:10

Translesion DNA Polymerases

11.2K
Translesion (TLS) polymerases rescue stalled DNA polymerases at sites of damaged bases by replacing the replicative polymerase and installing a nucleotide across the damaged site. Doing so, TLS allows additional time for the cell to repair the damage before resuming regular DNA replication.
TLS polymerases are found in all three domains of life - archaea, bacteria, and eukaryotes. Of the different classes of TLS polymerases, members of the Y family are fitted with specialized structures that...
11.2K
Le Chatelier's Principle: Changing Concentration02:27

Le Chatelier's Principle: Changing Concentration

66.1K
A system at equilibrium is in a state of dynamic balance, with forward and reverse reactions taking place at equal rates. If an equilibrium system is subjected to a change in conditions that affects these reaction rates differently (a stress), then the rates are no longer equal and the system is not at equilibrium. The system will subsequently experience a net reaction in the direction of a greater rate (a shift) that will re-establish the equilibrium. This phenomenon is summarized by Le...
66.1K
Le Chatelier's Principle: Changing Volume (Pressure)02:32

Le Chatelier's Principle: Changing Volume (Pressure)

40.7K
For gas-phase equilibria, changes in the concentrations of reactants and products can occur with altered volume and pressure. The partial pressure, P, of an ideal gas is proportional to its molar concentration, M.
40.7K
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

40.9K
Overview
40.9K
Restarting Stalled Replication Forks02:37

Restarting Stalled Replication Forks

6.4K
DNA replication is initiated at sites containing predefined DNA sequences known as origins of replication. DNA is unwound at these sites by the minichromosome maintenance (MCM) helicase and other factors such as Cdc45 and the associated GINS complex.The unwound single strands are protected by replication protein A (RPA) until DNA polymerase starts synthesizing DNA at the 5’ end of the strand in the same direction as the replication fork. To prevent the replication fork from falling apart,...
6.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Myofascial pain and dysfunction as predictors of tinnitus in adults: a case-control study.

Head & face medicine·2026
Same author

Artificial intelligence for skeletal classification in orthodontics: A systematic review and meta-analysis of lateral cephalometric studies.

Journal of Taibah University Medical Sciences·2026
Same author

Understanding the Content and Purpose of S3 Clinical Practice Guidelines in Dentistry.

International endodontic journal·2026
Same author

AI-assisted Software Development in Digital Dentistry: A Technical Innovation Report with Three Open-Source Applications.

Journal of dentistry·2026
Same author

Predicting Perceived Profile Attractiveness From Cephalometric Measurements Using Machine Learning.

International dental journal·2026
Same author

Diagnosis and Dentists' Treatment Preferences for Vestibular Enamel Defects-A Cross-Sectional Survey.

Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]·2026

Related Experiment Video

Updated: Feb 10, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

3.5K

Restoring the Carious Lesion.

Gerd Göstemeyer, Falk Schwendicke, Uwe Blunck

    Monographs in Oral Science
    |May 26, 2018
    PubMed
    Summary

    Restoring deep cavities requires careful consideration of factors affecting pulp vitality and adhesive bonding to dentin. This chapter offers guidance on material selection and techniques for long-lasting restorations.

    Area of Science:

    • Restorative Dentistry
    • Dental Materials Science
    • Cariology

    Background:

    • Restoring deep carious lesions, particularly those near the pulp, presents significant clinical challenges.
    • Restoration longevity is influenced by various intra-operative and material-related factors.

    Purpose of the Study:

    • To discuss critical aspects for successful restoration of carious lesions.
    • To review factors impacting pulp vitality and adhesive bonding to dentin.
    • To provide recommendations for material and technique selection in restorative dentistry.

    Main Methods:

    • Literature review and synthesis of current knowledge on restorative challenges.
    • Discussion of factors affecting pulp health during cavity preparation and restoration.
    • Analysis of adhesive bonding principles and limitations to sound and carious dentin.

    More Related Videos

    Comparative Lesions Analysis Through a Targeted Sequencing Approach
    08:16

    Comparative Lesions Analysis Through a Targeted Sequencing Approach

    Published on: November 5, 2019

    7.3K
    Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
    03:37

    Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry

    Published on: June 6, 2025

    471

    Related Experiment Videos

    Last Updated: Feb 10, 2026

    Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
    07:30

    Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

    Published on: April 23, 2021

    3.5K
    Comparative Lesions Analysis Through a Targeted Sequencing Approach
    08:16

    Comparative Lesions Analysis Through a Targeted Sequencing Approach

    Published on: November 5, 2019

    7.3K
    Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
    03:37

    Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry

    Published on: June 6, 2025

    471

    Main Results:

    • Preparation trauma, tooth hypersensitivity, and liner use can affect pulp vitality.
    • Adhesive bonding to dentin, both sound and carious, has inherent challenges and limitations.
    • Different bonding techniques and restorative materials have varying suitability depending on the clinical situation.

    Conclusions:

    • Successful restoration of deep carious lesions necessitates a comprehensive approach considering pulpal and adhesive factors.
    • Evidence-based recommendations for material and technique selection can enhance restoration longevity.
    • Understanding the interplay between preparation, bonding, and materials is crucial for predictable clinical outcomes.