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Relative Suffix Trees.

Andrea Farruggia1, Travis Gagie2,3, Gonzalo Navarro2,4

  • 1Department of Computer Science, University of Pisa, Largo Bruno Pontecorvo 3, 56127 Pisa PI, Italy.

The Computer Journal
|May 26, 2018
PubMed
Summary
This summary is machine-generated.

We introduce a novel method for compressing suffix trees in repetitive sequence collections by referencing a common suffix tree. This approach significantly reduces space usage while maintaining competitive query times for bioinformatics applications.

Keywords:
compressed text indexingrepetitive collectionssuffix trees

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Area of Science:

  • Stringology
  • Bioinformatics
  • Data Structures

Background:

  • Suffix trees are essential in stringology and bioinformatics but suffer from large memory footprints.
  • Compressed suffix trees aim to reduce space complexity while simulating full suffix tree functionality.
  • Repetitive sequence collections, like multiple genomes, pose unique challenges for suffix tree compression.

Purpose of the Study:

  • To develop a new approach for compressing suffix trees tailored to repetitive sequence collections.
  • To compress individual suffix trees relative to a reference sequence's suffix tree.
  • To achieve competitive time and space trade-offs for compressed suffix trees in this context.

Main Methods:

  • Developing a relative compression strategy for suffix trees.
  • Utilizing a reference sequence's suffix tree as a basis for compression.
  • Evaluating the performance of these relative compressed suffix trees.

Main Results:

  • The proposed relative data structures achieve space usage comparable to the smallest compressed suffix trees for repetitive collections.
  • The method offers query times competitive with the largest and fastest compressed suffix trees.
  • Demonstrated effective compression for collections of individual genomes.

Conclusions:

  • Relative compression of suffix trees offers an efficient solution for handling repetitive sequence collections in bioinformatics.
  • This approach balances space reduction with computational efficiency.
  • The method presents a viable alternative for large-scale genomic data analysis.