Related Experiment Video
Updated: Feb 10, 2026

Production and Characterization of Vacuum Deposited Organic Light Emitting Diodes
Published on: November 16, 2018
Helicobacter pylori Eradication Using a Light-Emitting Diode and Methylene Blue
1Sarufutsu Village National Health Insurance Hospital.
Background And Aims:
Eradication failures are increasing with the increasing antibiotic resistance of Helicobacter pylori.We examined the basic effect of methylene blue (MB) with sodium bicarbonate (NaHCO3) on H. pylori eradication using antimicrobial chemotherapy activated by light.
Material And Methods:
When NaHCO3 was added to MB, the pH became basic. We smeared H. pylori on a medium with basic MB and irradiated it using a red light-emitting diode with a wavelength of 660 nm. The applied energy fluencies were 10 J/cm2 and 15 J/cm2. After 4 days of culture, the effect of this intervention was determined according to the bacterial growth area.
Results:
The basic effect of MB appeared between a pH of 8.6 and 9.0. The NaHCO3 concentration was between 4% and 6%. The basic effect at 15 J/cm2 was greater than that at 10 J/cm2.
Conclusions:
We concluded that antimicrobial chemotherapy activated by light with basic MB was effective in H. pylori eradication.
More Related Videos
Related Concept Videos
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
Zener Diodes
The Ideal Diode
Diode: Forward bias
The behavior of a diode in forward bias...
Modeling of Diode Forward Characteristics
Light as Energy
Photons
A photon is a discrete electromagnetic particle or bundle of energy. Photons are characterized by their frequency, wavelength, and amplitude, similar to the properties of a wave. Waves with higher frequencies transmit more energy and have shorter wavelengths than longer wavelengths that transmit...

