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Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia

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Published on: October 25, 2016

Self-reported sex differences in high-functioning adults with autism: a meta-analysis.

R L Moseley¹, R Hitchiner¹, J A Kirkby¹

¹Department of Psychology, Bournemouth University, Fern Barrow, Poole, Dorset, BH12 5BB UK.

Molecular Autism

|May 26, 2018

Summary

Autistic adults show sex differences in symptoms, with males reporting more social and interest-based symptoms, while autistic women report more sensorimotor symptoms. These findings highlight the importance of considering sex differences in autism spectrum condition diagnosis.

Keywords:

Gender RAADS-R Self-report Sex

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Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

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Published on: April 22, 2015

Area of Science:

Neuroscience
Psychology
Genetics

Background:

Sex differences in autism spectrum condition (ASC) symptomatology contribute to underdiagnosis in females.
While childhood sex differences are increasingly studied, adult differences remain less understood.

Purpose of the Study:

To investigate sex differences in adult autism symptomatology using the Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R).
To analyze RAADS-R data through meta-analysis and ANOVA to identify main effects of sex and diagnosis, and their interactions.

Main Methods:

Meta-analysis of RAADS-R data from multiple experimental groups.
Analysis of variance (ANOVA) to examine effects of sex, diagnosis, and their interaction on symptomatology.

Main Results:

Autistic adults reported higher symptom prevalence in social relatedness and circumscribed interests compared to non-autistic adults.
Males generally reported more prevalent symptoms in circumscribed interests than females.
Language difficulties showed attenuated sex differences in autistic individuals.
Sensorimotor symptoms were more prevalent in autistic women than autistic men, unlike in the typically developing population.

Conclusions:

Childhood sex differences in autism may not persist into adulthood, potentially due to diagnostic biases favoring male-like presentations in women.
Sensorimotor symptomatology in autistic women warrants further investigation for diagnostic utility.
Understanding adult sex differences in ASC is crucial for improving diagnostic accuracy and support.