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Updated: Feb 10, 2026

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
Published on: January 8, 2013
True vs. pseudo-electrical ventricular alternans sustained by ventricular premature complexes
S S Barold1, K Rajamani2, A Kucher3
1Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. ssbarold@aol.com.
Abstract:
This report describes a form of electrical ventricular alternans sustained by ventricular premature complexes (VPC). Alternans was associated with a constant heart rate (RR interval) and was therefore considered to be either a form of classic or true alternans or a mimic of the configuration seen in true alternans from other causes. In contrast, VPC-induced pseudo-alternans is characterized by an inconstant heart rate (RR interval). It is surprising that the incidence of true VPC-induced alternans is unappreciated and virtually unreported, most probably since the measurement of the RR intervals involving late VPCs is ignored.
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