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Updated: Feb 10, 2026

Perspectives on Neuroscience
Published on: July 31, 2007
White-coat hypertension from a paediatric perspective
1Department of Physiology and Pharmacology (FYFA), C3, Karolinska Institutet, Stockholm, Sweden.
Insights
White-coat hypertension (WCH) is common in children, showing high office blood pressure (BP) but normal ambulatory BP monitoring (ABPM). ABPM is crucial for accurate diagnosis and management in pediatric hypertension.
Area of Science:
- Pediatric Cardiology
- Hypertension Research
- Clinical Diagnostics
Background:
- White-coat hypertension (WCH) is a prevalent condition in pediatric populations.
- WCH is characterized by elevated office blood pressure (BP) readings contrasted with normal BP during ambulatory monitoring.
- Accurate BP measurement is vital for diagnosing and managing pediatric hypertension.
Purpose of the Study:
- To review the prevalence and diagnostic methods for white-coat hypertension in children.
- To provide an overview of current pediatric data on WCH.
- To emphasize the importance of ambulatory BP monitoring (ABPM) in pediatric hypertension management.
Main Methods:
- Comparative analysis of office BP readings and 24-hour ambulatory BP monitoring (ABPM).
- Review of existing literature on WCH in adult and pediatric populations.
- Focus on diagnostic criteria and clinical implications of WCH in children.
Main Results:
- WCH is identified by comparing elevated office BP with normal ABPM readings.
- Ambulatory BP monitoring (ABPM) provides a more accurate assessment of a child's BP than traditional office readings.
- Identifying WCH in children is critical for appropriate cardiovascular risk management.
Conclusions:
- Ambulatory BP monitoring (ABPM) is the gold standard for diagnosing WCH in pediatric patients.
- Accurate BP evaluation through ABPM aids in precise diagnosis and management of pediatric hypertension.
- Early identification of WCH and associated risk factors like obesity is essential for long-term cardiovascular health in children.
Aim:
This mini review explored the prevalence of white-coat hypertension (WCH), which is very common in children. It results in elevated office blood pressure (BP) but normal ambulatory BP monitoring (ABPM) readings.
Methods:
WCH can only be identified by analysing and comparing office BP readings and ABPM, which periodically records BP every 20-30 minutes over 24-hour period. This study provides initially the background for WCH in adults, together with a comprehensive overview of the most relevant paediatric data on WCH.
Results:
Accurate measurements of BP are very important for the diagnosis and management of hypertension. It is important to acknowledge the clinical relevance of WCH and follow up children who display this BP phenotype by carrying out ABPM, so that clinicians can build up an accurate picture of their BP. It is also important to identify children who have BP issues and are overweight or obese, so that treatment of this modifiable cardiovascular risk factor can be initiated.
Conclusion:
Using ABPM provides paediatricians with a more precise evaluation of a child's BP readings than office BP readings. It is the gold standard for diagnosing WCH.
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