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Updated: Feb 10, 2026

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
Published on: February 9, 2020
Intracranial, extraneural ectopic lymph node in a bovine (Bos taurus)
Chad S Clancy1, Arnaud J Van Wettere1, Gordon A Hullinger1
1Utah State Veterinary Diagnostic Laboratory, Department of Animal, Dairy and Veterinary Science, Utah State University, Logan, Utah.
Abstract:
The brain from a field necropsied 8-month-old feedlot heifer presenting with an acute history of depression, lethargy, dyspnoea and anorexia was evaluated grossly and by histopathology. The meninges overlying the left cerebral hemisphere contained a 12 × 26 × 32 mm, dark red, soft, ovoid mass. Histologic examination of this tissue revealed a well-organized lymph node with normal architecture. Organization of reactive lymphoid tissue resembling normal lymph node architecture may occur under chronic stimulation. However, there are no known aggregates of lymphoid tissue present within the cranial vault in any veterinary species. This is the first reported case of an intracranial ectopic lymph node in any species.
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