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Doppler Optical Coherence Tomography of Retinal Circulation
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Adaptable switching schemes for time-encoded multichannel optical coherence tomography.

Andreas Wartak1, Florian Beer1,2, Bernhard Baumann1

  • 1Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria.

Journal of Biomedical Optics
|May 26, 2018
PubMed
Summary

Variable time encoding enhances multichannel optical coherence tomography (OCT) sensitivity, particularly for retinal imaging. This method overcomes reduced imaging speed and Doppler velocity limitations, improving image quality and diagnostic capabilities.

Keywords:
Dopplerophthalmologyoptical coherence tomographyoptical switchingretinal imaging

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Area of Science:

  • Ophthalmic imaging
  • Biomedical optics
  • Medical instrumentation

Background:

  • Multichannel optical coherence tomography (OCT) typically divides illumination power for laser safety, potentially reducing image sensitivity.
  • Simultaneous illumination in multichannel OCT can compromise image quality due to power division.

Purpose of the Study:

  • To introduce and validate a variable time encoding approach for multichannel OCT.
  • To enhance image quality and sensitivity in OCT, especially for ophthalmic applications like retinal imaging.
  • To address and overcome the limitations of reduced imaging speed and Doppler velocity in time-encoded OCT.

Main Methods:

  • Utilized high-speed fiber optical switches for sequential sample arm switching in multichannel OCT.
  • Implemented a variable time encoding strategy for quasisimultaneous image acquisition from multiple angles.
  • Adapted the illumination channel switching scheme to mitigate reduced Doppler velocity limitations.

Main Results:

  • Variable time encoding improved OCT sensitivity by eliminating the need for illumination power division, crucial for retinal imaging.
  • Demonstrated that adapted switching schemes can overcome the reduction in maximum unambiguously determinable Doppler frequency.
  • Achieved re-extension of the maximum unambiguously determinable Doppler frequency to the full A-scan rate.

Conclusions:

  • Variable time encoding is a viable strategy for enhancing multichannel OCT sensitivity and image quality, particularly in ophthalmic applications.
  • The presented method effectively overcomes the trade-off between sensitivity and imaging speed inherent in traditional multichannel OCT.
  • The technique shows promise for improved retinal blood flow measurements and other diagnostic applications using OCT.