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[Differences in clinical features of post-traumatic olfactory dysfunction and non-post-traumatic olfactory

Y F Liu1, L Y Yao1, Y C Guo1

  • 1Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, 100029, China.

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery
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Summary

Post-traumatic olfactory dysfunction (PTOD) affects younger adults and has a low recovery rate, with olfactory function improving more than gustatory function. Understanding PTOD is crucial for diagnosis and treatment.

Keywords:
clinical featuresgustatory functionhospital-based follow-up studyolfactory functionpost-traumatic olfactory dysfunction

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Area of Science:

  • Otorhinolaryngology
  • Neurology
  • Clinical Research

Background:

  • Post-traumatic olfactory dysfunction (PTOD) is a significant condition impacting quality of life.
  • Understanding the clinical characteristics and recovery patterns of PTOD is essential for effective management.

Purpose of the Study:

  • To analyze the clinical features of PTOD in Chinese adults.
  • To determine the recovery rate of olfactory and gustatory functions in PTOD patients.

Main Methods:

  • A case-control follow-up study involving 202 patients with olfactory dysfunction.
  • Comparison of clinical data, olfactory and gustatory function tests (Sniffin' sticks, triple drop method), chemosensory evoked potentials, and MRI between PTOD and non-PTOD groups.
  • Evaluation of recovery rates over a 14 to 473-day follow-up period.

Main Results:

  • PTOD patients were significantly younger (40±11 years) than non-PTOD patients (47±15 years).
  • Significant differences were observed in TDI scores and oERP P2 latency between the groups.
  • Low recovery rates were noted: 8.9% for olfactory function and 5.4% for gustatory function.

Conclusions:

  • PTOD is a critical condition that warrants thorough understanding for diagnosis and treatment.
  • Olfactory function recovery is more common than gustatory function recovery in PTOD patients.
  • Further research is needed to explore PTOD recovery mechanisms and improve treatment outcomes.