[Efficiency of oral administration of glucocorticosteroid for treating nasal inflammation]
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Abstract:
The pathological basis of nasal inflammation is still not well defined. Extensive studies showed the immune response mediated by T cells played an important role in the pathogenesis of nasal inflammation. The inflammation in the nasal membrane could be considered as the common routines for the development of chronic sinusitis(CRS), allergic rhinitis and allergic fungal sinusitis.Glucocorticosteroid, a compound with similar structure with the adrenal cortical hormone, has been commonly used for the treatment of nasal inflammation. To date, its efficiency via nasal membrane has been well acknowledged in clinical practice, while the efficiency of oral administration is still not well defined. In this study, we aim to investigate the efficiency of oral administration of glucocorticosteroid for treating nasal inflammation.
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