Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

1.1K
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
1.1K
Buffer Effectiveness02:19

Buffer Effectiveness

55.5K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
55.5K
Framing Effects03:26

Framing Effects

8.0K
Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in...
8.0K
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

231
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
231
Design Example: Calculating Safe Diameter for Wind-Exposed Disc01:17

Design Example: Calculating Safe Diameter for Wind-Exposed Disc

363
Assessing safety in wind-exposed installations is crucial to preventing potential failures. This example explores the calculation and design adjustments needed to mount a circular disc on a building facade, where wind forces are a primary concern. A 4-meter diameter disc was initially designed as an aesthetic feature facing winds at a velocity of 25 meters per second, with an air density of 1.25 kilograms per cubic meter. Given these conditions, the drag force on the disc was determined using...
363
Biological Effects of Radiation02:59

Biological Effects of Radiation

18.0K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
18.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomechanical comparison of two-screw and four-screw zero-profile fusion devices in anterior cervical discectomy and fusion using finite element analysis.

Scientific reports·2026
Same author

The effect of low muscle mass on neck disorder and cervical movement kinematics in university students: A comparative study.

Clinical biomechanics (Bristol, Avon)·2026
Same author

Non-contiguous three-level hybrid surgery with C2-3 cervical disc arthroplasty: a case report and literature review.

Frontiers in surgery·2025
Same author

Development and Validation of an Interpretable Machine Learning Model for Predicting Early Fusion After Anterior Cervical Discectomy and Fusion.

Spine·2025
Same author

Anterior Cervical X-Shape-Corpectomy and Fusion Versus Anterior Cervical Corpectomy and Fusion for Cervical Spondylotic Myelopathy: A Prospective Randomized Controlled Trial.

Global spine journal·2025
Same author

To What Extent Do Different Criteria Influence 3-Month Fusion Evaluation in Anterior Cervical Arthrodesis Trials?

Orthopaedic surgery·2025

Related Experiment Video

Updated: Feb 10, 2026

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
20:36

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

9.2K

[Early effectiveness of cervical disc replacement by using Pretic-I].

Hao Liu1, Yuxiao Deng2, Ziyang Liu2

  • 1Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.liuhao6304@163.com.

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery
|May 26, 2018
PubMed
Summary

Cervical disc replacement with the new Pretic-I artificial disc shows satisfactory early effectiveness. Patients experienced significant symptom relief and maintained motion at operated and adjacent levels.

Keywords:
Pretic-I artificial disccervical disc herniationcervical disc replacement

More Related Videos

Anterior Cervical Discectomy and Fusion in the Ovine Model
06:11

Anterior Cervical Discectomy and Fusion in the Ovine Model

Published on: October 5, 2009

13.3K
Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster
10:10

Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster

Published on: September 20, 2014

27.7K

Related Experiment Videos

Last Updated: Feb 10, 2026

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
20:36

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

9.2K
Anterior Cervical Discectomy and Fusion in the Ovine Model
06:11

Anterior Cervical Discectomy and Fusion in the Ovine Model

Published on: October 5, 2009

13.3K
Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster
10:10

Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster

Published on: September 20, 2014

27.7K

Area of Science:

  • Orthopedic Surgery
  • Spinal Surgery
  • Biomaterials Science

Background:

  • Cervical disc degeneration is a common condition causing pain and disability.
  • Artificial disc replacement aims to preserve motion and reduce adjacent segment degeneration compared to fusion.
  • The Pretic-I is a novel artificial disc for cervical spine applications.

Purpose of the Study:

  • To evaluate the early clinical effectiveness and safety of the Pretic-I artificial disc in patients undergoing cervical disc replacement.
  • To assess the impact of Pretic-I on pain, function, and spinal biomechanics.

Main Methods:

  • Retrospective analysis of 10 patients who underwent single-level cervical disc replacement with Pretic-I.
  • Clinical outcomes assessed using Visual Analogue Scale (VAS), Japanese Orthopaedic Association (JOA) score, and Neck Disability Index (NDI).
  • Radiographic evaluation included disc height and range of motion (ROM) at the operated and adjacent levels.

Main Results:

  • All 10 patients completed 12-month follow-up without major complications.
  • Significant improvements in VAS, JOA scores, and NDI were observed post-operatively (P<0.05).
  • Disc height at the operated level increased initially, while ROM at operated and adjacent levels remained stable.

Conclusions:

  • Cervical disc replacement with the Pretic-I artificial disc demonstrates satisfactory early effectiveness.
  • The procedure effectively relieves symptoms and preserves the dynamic function of the cervical spine.
  • Pretic-I shows promise for managing cervical disc degeneration while maintaining spinal mobility.