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Updated: Feb 10, 2026

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
[Intussusception followed by intestinal obstruction in adults]
A V Pugaev1, E E Achkasov1, M G Negrebov1
1Martynov Chair of Hospital-Based Surgery # 1, Sechenov First Moscow State Medical University of Healthcare Ministry of the Russian Federation, Vorokhobov Municipal City Clinical Hospital No. 67 Moscow Healthcare Department, Moscow, Russia.
Preoperative diagnostics and medication effectively identified adult intussusception with intestinal obstruction in 86.7% of cases. Surgical repair outcomes varied based on the underlying cause, highlighting the importance of timely intervention for better results.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Abdominal Surgery
Background:
- Intussusception leading to intestinal obstruction is a rare but serious condition in adults.
- Accurate preoperative diagnosis and management are crucial for successful surgical outcomes.
- Identifying the underlying cause of intussusception is key to tailoring treatment strategies.
Purpose of the Study:
- To assess the efficacy of preoperative diagnostics and medication for adult intussusception with intestinal obstruction.
- To evaluate surgical repair strategies and analyze outcomes based on the etiology of intussusception.
- To identify factors influencing postoperative complications and mortality.
Main Methods:
- A cohort of 15 adult patients with intussusception and intestinal obstruction was studied.
- Diagnosis involved clinical evaluation, abdominal X-ray, and ultrasound.
- Surgical interventions included small intestine resection, hemicolectomy, and sigmoid colon resection.
Main Results:
- Preoperative diagnostics and medication successfully identified intussusception in 86.7% of patients before surgery.
- Epithelial and stromal tumors were the most common cause (9 patients), followed by melanoma metastasis (2 patients).
- Postoperative complications were more frequent in high-risk patients with delayed hospitalization and comorbidities; one patient died.
Conclusions:
- Complex preoperative assessment and management improve the detection rate of intussusception causing intestinal obstruction in adults.
- Surgical outcomes are significantly influenced by the underlying cause of intussusception, with tumors being a frequent etiology.
- Prompt surgical intervention and management of comorbidities are vital for reducing postoperative complications and mortality in these patients.
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