Applying the phenotype approach for rosacea to practice and research

Area of Science:

• Dermatology
• Clinical Science
• Medical Research

Background:

• Rosacea classification has evolved from the 2002 National Rosacea Society expert panel subtype approach.
• Current trends favor a patient-centric phenotype approach based on individual signs and symptoms.
• Subtyping remains prevalent, necessitating a unified strategy for phenotype approach adoption.

Purpose of the Study:

• To offer practical recommendations for adopting a phenotype approach in rosacea research and clinical practice.
• To facilitate the transition from traditional subtyping to a more individualized patient assessment.

Main Methods:

• Literature review to synthesize existing knowledge on rosacea classification.
• Consolidation of expert experience to identify implementation challenges and solutions.

Main Results:

• Identified key challenges in implementing a phenotype approach for rosacea.
• Developed practical recommendations to overcome these challenges in clinical practice and research.

Conclusions:

• Recommendations guide the progression from subtyping to a phenotype approach in rosacea.
• Aims to enhance disease understanding, accelerate treatment development, and improve patient outcomes.