Related Experiment Video
Updated: Feb 10, 2026
09:12
A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia
Published on: February 3, 2023
3.3K
[Colorimetric card use for early detection visual biliary atresia]
Alicia Reyes-Cerecedo1, Judith Flores-Calderón1, Miguel Á Villasis-Keever2
1Servicio de Gastroenterología. Ciudad de México, México.
Boletin Medico Del Hospital Infantil De Mexico
|May 26, 2018
Summary
The visual colorimetric card (VVC) did not improve timely detection of biliary atresia (BVA) in Mexico after its incorporation into the National Health Card. Further program reinforcement is needed across all healthcare levels.
Area of Science:
- Pediatric Gastroenterology
- Neonatal Surgery
- Public Health Initiatives
Background:
- Bile duct atresia (BVA) is a critical neonatal condition leading to cirrhosis and early death if uncorrected.
- The visual colorimetric card (VVC) was implemented in Mexico in 2013 to aid early BVA detection via the National Health Card (NHC).
Purpose of the Study:
- To assess the impact of the VVC on the timely diagnosis and surgical intervention for BVA.
- To evaluate changes in patient referral, diagnosis, and surgery timelines before and after NHC incorporation of the VVC.
Main Methods:
- An ambispective, analytical observational study was conducted.
- Data from 59 BVA patients treated in two tertiary pediatric hospitals were analyzed.
- Parental perception of the VVC was gathered through a questionnaire.
Main Results:
- No significant difference was observed in the age at diagnosis (75 vs. 70 days) or surgery (84 vs. 90 days) post-VVC implementation.
- Only 30% of parents received VVC information, and 38% could identify abnormal stools.
Conclusions:
- The VVC, as implemented, did not demonstrably improve the timeliness of BVA detection.
- Strengthening the VVC program across all healthcare levels in Mexico is essential for enhancing early BVA diagnosis.
Related Concept Videos
01:26Visual System
1.8K
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Once through the pupil, the light passes through the lens, a...
1.8K
01:12Visual Agnosia
1.1K
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
1.1K
01:22Photoreceptors and Visual Pathways
9.3K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
9.3K
01:00Detection of Gross Error: The Q Test
7.0K
When one or more data points appear far from the rest of the data, there is a need to determine whether they are outliers and whether they should be eliminated from the data set to ensure an accurate representation of the measured value. In many cases, outliers arise from gross errors (or human errors) and do not accurately reflect the underlying phenomenon. In some cases, however, these apparent outliers reflect true phenomenological differences. In these cases, we can use statistical methods...
7.0K
01:10Detection of Black Holes
2.6K
Although black holes were theoretically postulated in the 1920s, they remained outside the domain of observational astronomy until the 1970s.
Their closest cousins are neutron stars, which are composed almost entirely of neutrons packed against each other, making them extremely dense. A neutron star has the same mass as the Sun but its diameter is only a few kilometers. Therefore, the escape velocity from their surface is close to the speed of light.
Not until the 1960s, when the first neutron...
Their closest cousins are neutron stars, which are composed almost entirely of neutrons packed against each other, making them extremely dense. A neutron star has the same mass as the Sun but its diameter is only a few kilometers. Therefore, the escape velocity from their surface is close to the speed of light.
Not until the 1960s, when the first neutron...
2.6K
01:05Difference from Background: Limit of Detection
8.4K
The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
The LOD indicates the presence or absence...
8.4K