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Updated: Feb 10, 2026
04:23
A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
Published on: April 21, 2023
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Elastography in the evaluation of thyroid nodules
Carlos Paredes-Manjarrez1, Andrés Magdalena-Buitrago, Gamaliel Meza-Hernández
1Departamento de Radiología e Imagen, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México carlos.paredes.manjarrez@gmail.com
Summary
Elastography aids in assessing thyroid nodule malignancy risk, with qualitative methods showing higher sensitivity and semi-quantitative methods higher specificity. These techniques supplement ultrasound but do not replace cytopathology for definitive diagnosis.
Area of Science:
- Radiology
- Oncology
- Endocrinology
Background:
- Thyroid nodules are highly prevalent, with up to 50% of asymptomatic individuals over 1 cm.
- Distinguishing benign from malignant nodules is crucial for patient management.
Purpose of the Study:
- To evaluate the diagnostic accuracy of elastography in identifying malignant thyroid nodules.
- To compare qualitative and semi-quantitative elastography with fine-needle aspiration biopsy (FNAB) and histopathology.
Main Methods:
- Inclusion of adult patients (≥18 years) with diagnosed thyroid nodules undergoing ultrasound-guided FNAB.
- Statistical analysis included sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV).
Main Results:
- Qualitative elastography (Asteria Score): 86% sensitivity, 53% specificity, 36% PPV, 92% NPV.
- Semi-quantitative elastography: 40% sensitivity, 87% specificity, 50% PPV, 82% NPV.
Conclusions:
- Elastography is a valuable adjunct to ultrasound for assessing thyroid nodule malignancy risk.
- Neither qualitative nor semi-quantitative elastography should be used as a standalone diagnostic test; cytopathology remains essential.
- A high NPV for qualitative elastography is useful for ruling out malignancy.
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