Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Incomplete Dominance01:43

Incomplete Dominance

30.1K
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
30.1K
Divergence and Curl01:15

Divergence and Curl

3.2K
The divergence of a vector field at a point is the net outward flow of the flux out of a small volume through a closed surface enclosing the volume, as the volume tends to zero. More practically, divergence measures how much a vector field spreads out or diverges from a given point. For an outgoing flux, conventionally, the divergence is positive. The diverging point is often called the "source" of the field. Meanwhile, the negative divergence of a vector field at a point means that the vector...
3.2K
Divergence and Stokes' Theorems01:06

Divergence and Stokes' Theorems

3.7K
The divergence and Stokes' theorems are a variation of Green's theorem in a higher dimension. They are also a generalization of the fundamental theorem of calculus. The divergence theorem and Stokes' theorem are in a way similar to each other; The divergence theorem relates to the dot product of a vector, while Stokes' theorem relates to the curl of a vector. Many applications in physics and engineering make use of the divergence and Stokes' theorems, enabling us to write...
3.7K
Gene Duplication and Divergence02:37

Gene Duplication and Divergence

8.0K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
8.0K
Lineage Commitment01:21

Lineage Commitment

4.4K
Commitment is the  process whereby stem cells:
4.4K
Divergence and Curl of Electric Field01:25

Divergence and Curl of Electric Field

7.3K
The divergence of a vector is a measure of how much the vector spreads out (diverges) from a point. For example, an electric field vector diverges from the positive charge and converges at the negative charge. The divergence of an electric field is derived using Gauss's law and is equal to the charge density divided by the permittivity of space. Mathematically, it is expressed as
7.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of metabolic dysfunction-associated fatty liver disease in primary care: a consensus statement summary.

The Medical journal of Australia·2025
Same author

Quantitation of Tapentadol by Liquid Chromatography: Tandem Mass Spectrometry.

Methods in molecular biology (Clifton, N.J.)·2018
Same author

At-a-glance - The role of opioid toxicity in suicide deaths in Alberta, 2000 to 2016.

Health promotion and chronic disease prevention in Canada : research, policy and practice·2018
Same author

Interpreting insulin immunoassays during investigation of apparent spontaneous hypoglycaemia and insulin overdose.

Internal medicine journal·2017
Same author

Guidance concerning the use of glycated haemoglobin (HbA1c) for the diagnosis of diabetes mellitus.

The Medical journal of Australia·2015
Same author

Deaths from exposure to paramethoxymethamphetamine in Alberta and British Columbia, Canada: a case series.

CMAJ open·2015

Related Experiment Video

Updated: Feb 10, 2026

Co-localization of Cell Lineage Markers and the Tomato Signal
10:56

Co-localization of Cell Lineage Markers and the Tomato Signal

Published on: December 28, 2016

12.8K

Divergence Estimation in the Presence of Incomplete Lineage Sorting and Migration.

Graham R Jones1

  • 1Department of Biological and Environmental Sciences, University of Gothenburg, Box 461, SE 405 30 Göteborg, Sweden.

Systematic Biology
|May 26, 2018
PubMed
Summary

Estimating species trees with incomplete lineage sorting and migration is challenging. A new method, DENIM (Divergence estimation notwithstanding ILS and migration), improves accuracy by modeling these evolutionary processes.

More Related Videos

Isolation of Lung Retinoid-Containing Cells by Cell Sorting
07:47

Isolation of Lung Retinoid-Containing Cells by Cell Sorting

Published on: April 11, 2025

716
Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors
12:03

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors

Published on: July 8, 2012

19.3K

Related Experiment Videos

Last Updated: Feb 10, 2026

Co-localization of Cell Lineage Markers and the Tomato Signal
10:56

Co-localization of Cell Lineage Markers and the Tomato Signal

Published on: December 28, 2016

12.8K
Isolation of Lung Retinoid-Containing Cells by Cell Sorting
07:47

Isolation of Lung Retinoid-Containing Cells by Cell Sorting

Published on: April 11, 2025

716
Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors
12:03

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors

Published on: July 8, 2012

19.3K

Area of Science:

  • Evolutionary biology
  • Phylogenetics
  • Population genetics

Background:

  • Estimating species trees from multilocus data is complex due to incomplete lineage sorting (ILS) and migration.
  • Standard multispecies coalescent models can yield inaccurate species tree inferences when migration is present.

Purpose of the Study:

  • To develop a novel mathematical model and associated software package (DENIM) for species tree estimation that accounts for ILS and migration.
  • To evaluate the performance of DENIM using simulated and empirical data, comparing it against existing methods.

Main Methods:

  • Development of a mathematical model integrating population size and migration parameters.
  • Implementation of the DENIM package in BEAST2, utilizing an approximation for posterior sampling under rare migration assumptions.
  • Reanalysis of simulated data from Leaché et al. (2014) and an empirical dataset.

Main Results:

  • DENIM demonstrates substantial improvements in species tree inference accuracy compared to *BEAST on simulated data with migration.
  • The model's approximation performs well under the assumption of rare migrations.
  • The method's limitations are noted when significant migration occurs.

Conclusions:

  • DENIM offers a more accurate approach to species tree estimation in the presence of ILS and migration, particularly when migration is infrequent.
  • The study highlights the importance of explicitly modeling migration for robust phylogenetic inference.
  • Further development may be needed to address scenarios with high migration rates.